Crooke Cell Adenoma Confers Poorer Endocrinological Outcomes Compared with Corticotroph Adenoma: Results of a Multicenter, International Analysis

MC Findlay, R Drexler, M Azab, A Karbe… - World Neurosurgery, 2023 - Elsevier
Background Crooke cell adenomas (CCAs) are a rare, aggressive subset of secretory
pituitary corticotroph adenomas (sCTAs) found in 5%–10% of patients with Cushing disease …

Molecular, functional, and histopathological classification of the pituitary neuroendocrine neoplasms

C Inomoto, S Tahara, K Oyama, M Kimura… - Brain Tumor …, 2021 - Springer
In 2017, WHO published an updated classification of the pituitary adenomas according to
the lineages defined by the transcription factors, PIT1, SF1 and TPIT. Nomenclature of the …

[HTML][HTML] Prognostic factors for surgical treatment of prolactin-secreting pituitary adenomas

O Voznyak, I Zinkevych, A Lytvynenko, N Hryniv… - Frontiers in …, 2024 - frontiersin.org
Introduction Usually, prolactinomas are treated with dopamine agonists (DA). Surgery is
considered an option when the patient cannot bear or does not respond positively to DA …

[HTML][HTML] Genome wide analysis of circulating miRNAs in growth hormone secreting pituitary neuroendocrine tumor patients' plasma

H Niedra, R Peculis, HD Litvina, K Megnis… - Frontiers in …, 2022 - frontiersin.org
Background Circulating plasma miRNAs have been increasingly studied in the field of
pituitary neuroendocrine tumor (PitNET) research. Our aim was to discover circulating …

Association of KDR (rs2071559, rs1870377), CFH (rs1061170, rs1410996) genes variants and serum levels with pituitary adenoma

A Bruzaite, G Gedvilaite, L Kriauciuniene… - … Genetics & Genomic …, 2024 - Wiley Online Library
Introduction Pituitary adenomas (PA) are slow‐growing, benign tumors that usually do not
metastasize to other body organs. Although they are referred to as benign, tumor growth can …

Transcription Factor Immunohistochemistry in the Classification of Pituitary Neuroendocrine Tumor/Adenoma: Proposal in a Limited-Resource Setting

R Sood, D Chatterjee, P Dutta… - Archives of pathology …, 2024 - meridian.allenpress.com
Context.—Pituitary neuroendocrine tumors/adenomas are common intracranial tumors that
require accurate subtyping because each tumor differs in its biologic behavior and response …

Clinical characteristics and therapeutic outcomes of acromegalic patients with giant growth hormone-secreting pituitary adenomas: a single-center study of 67 cases

M Chen, L Duan, H Miao, N Yu, S Yang, L Wang… - Pituitary, 2023 - Springer
Purpose Acromegalic patients with giant growth hormone-secreting pituitary adenomas
(GHPAs)(≥ 40 mm) are relatively rare, and their clinical characteristics and treatment …

Past, present, and future of therapies for pituitary neuroendocrine tumors: need for omics and drug repositioning guidance

B Aydin, E Yildirim, O Erdogan, KY Arga… - Omics: a journal of …, 2022 - liebertpub.com
Innovation roadmaps are important, because they encourage the actors in an innovation
ecosystem to creatively imagine multiple possible science future (s), while anticipating the …

PIT-EASY survey: validation of the European Pituitary Pathology Group proposal for reporting pituitary neuroendocrine tumors

MF Birtolo, A Jouinot, A Vasiljevic, C Boulagnon-Rombi… - Virchows Archiv, 2024 - Springer
The aim of this multicenter prospective survey called PIT-EASY was to assess the relevance
of the European Pituitary Pathology Group (EPPG) diagnostic tools for pituitary …

[HTML][HTML] Pituitary adenomas in the elderly: Retrospective comparative analysis of clinical/tumor features and surgical data by age group

P Rosinha, L Fonseca, C Amaral, I Ribeiro… - Medicine, 2022 - journals.lww.com
The increase in life expectancy along with technological advances has translated into a
higher number of pituitary adenomas (PA) diagnosed from the age of 65. In the elderly …