[HTML][HTML] Alzheimer's Disease as A Viral Infectious Disease: Revisiting the Infectious Hypothesis

F Bruno, P Abondio, R Bruno, L Ceraudo… - Ageing research …, 2023 - Elsevier
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
Two major forms of the disease exist: sporadic-the causes of which have not yet been fully …

[HTML][HTML] Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity

R Martínez-Mármol, R Giordano-Santini, E Kaulich… - Science …, 2023 - science.org
Numerous viruses use specialized surface molecules called fusogens to enter host cells.
Many of these viruses, including the severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Tissue specific signature of HHV-6 infection in ME/CFS

F Kasimir, D Toomey, Z Liu, AC Kaiping… - Frontiers in Molecular …, 2022 - frontiersin.org
First exposure to various human herpesviruses (HHVs) including HHV-6, HCMV and EBV
does not cause a life-threatening disease. In fact, most individuals are frequently unaware of …

[HTML][HTML] Epstein–Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments

O Shechter, DG Sausen, ES Gallo, H Dahari… - International Journal of …, 2022 - mdpi.com
Epstein–Barr virus (EBV) is one of eight known herpesviruses with the potential to infect
humans. Globally, it is estimated that between 90–95% of the population has been infected …

[HTML][HTML] Potential molecular mechanisms of chronic fatigue in long haul COVID and other viral diseases

CG Gottschalk, D Peterson, J Armstrong, K Knox… - Infectious agents and …, 2023 - Springer
Historically, COVID-19 emerges as one of the most devastating diseases of humankind,
which creates an unmanageable health crisis worldwide. Until now, this disease costs …

[HTML][HTML] Current state of human gene therapy: approved products and vectors

AY Shchaslyvyi, SV Antonenko, MG Tesliuk… - Pharmaceuticals, 2023 - mdpi.com
In the realm of gene therapy, a pivotal moment arrived with Paul Berg's groundbreaking
identification of the first recombinant DNA in 1972. This achievement set the stage for future …

[HTML][HTML] Deciphering antiviral efficacy of malaria box compounds against malaria exacerbating viral pathogens-Epstein Barr virus and SARS-CoV-2, an in silico study

O Indari, AK Singh, D Tiwari, HC Jha, AN Jha - Medicine in Drug Discovery, 2022 - Elsevier
In malaria endemic countries, coinfections and cotransmissions of different viral pathogens
are widely reported. Prior studies have shown that malaria can trigger the Epstein-Barr virus …

[HTML][HTML] Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses

TH Mulherkar, DJ Gómez, G Sandel, P Jain - Viruses, 2022 - mdpi.com
Dendritic cells (DCs) function as a link between innate and adaptive immune responses.
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …

[HTML][HTML] Understanding the role of membrane cholesterol upon Epstein Barr virus infection in astroglial cells

A Rani, M Tanwar, TP Verma, P Patra… - Frontiers in …, 2023 - frontiersin.org
Background EBV infection has long been postulated to trigger multiple sclerosis (MS) and
anti-EBV antibodies showed a consistent presence in MS patients. Previous reports from our …