[HTML][HTML] Capillary electrophoresis mass spectrometry-based untargeted metabolomics to approach disease diagnosis

M Mamani-Huanca, A Villaseñor… - TrAC Trends in …, 2023 - Elsevier
Metabolites are the final products of the metabolism and are, therefore, directly related to
phenotype. They constitute the metabolome of an organism. The wide diversity of the …

[HTML][HTML] High expression of HNRNPR in ESCA combined with 18F-FDG PET/CT metabolic parameters are novel biomarkers for preoperative diagnosis of ESCA

XY Liu, Y Gao, XY Kui, XS Liu, Y Zhang… - Journal of Translational …, 2022 - Springer
Background The aim of this study was to determine the expression and function of
heterogeneous nuclear ribonucleoprotein R (HNRNPR) in esophageal carcinoma (ESCA) …

[HTML][HTML] Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas—A Preliminary Study

K Skubisz, K Dąbkowski, E Samborowska… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a significant problem worldwide. Most cancers are
diagnosed at an advanced stage. Limited knowledge of the pathogenesis of pancreatic …

[HTML][HTML] Identification and Validation of a Prognostic Immune-Related Gene Signature in Esophageal Squamous Cell Carcinoma

K Xiong, Z Tao, Z Zhang, J Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Esophageal carcinoma (EC) is a common malignant cancer worldwide. Esophageal
squamous cell carcinoma (ESCC), the main type of EC, is difficult to treat because of the …

Simvastatin inhibits PD-L1 via ILF3 to enhance CD8+ T cell-mediated ferroptosis in gastric cancer cells

D Sun, X Cui, W Yang, M Wei, Z Yan, M Zhang, Z Wang… - 2024 - researchsquare.com
Background Immunotherapy is vital in the comprehensive treatment of gastric cancer (GC).
However, the prognosis of GC patients remains unfavorable, necessitating to exploration of …

Metabolomics and transcriptomics joint analysis reveals altered amino acid metabolism in esophageal squamous cell carcinoma

Y Chen, H Yang, X Huang, R Wang, W Mao, Z Chen - 2023 - researchsquare.com
Objectives This study aims to explore the altered metabolic pathways for ESCC through joint-
pathway analysis of differentially expressed metabolites and genes. Methods Differentially …

Quantifying protein expression and activity complements genetics to optimize the use of targeted therapies in precision oncology

C Sobsey - 2023 - escholarship.mcgill.ca
La voie biochimique de la phosphatidylinositol-3-kinase (PI3K) est l'une des voies les plus
souvent dérégulées dans le cancer et la cible de nombreux nouveaux médicaments. Le …

Identificación y caracterización del proteoma involucrado en la regulación de la entrada de calcio operada por reservorios internos (SOCE) en células no excitables

RA Santos Alfaro - 2023 - repositorio.uchile.cl
La entrada de Ca2+ operada por reservorios internos (SOCE) es el mecanismo principal
para regular las señales de Ca2+ en células no excitables. Las proteínas STIM1, ORAI1 y …

Comprehensive Analysis of HNRNPR in ESCA and its High Expression Combined with 18F-FDG PET/CT Metabolic Parameters as a Novel Biomarker for ESCA …

XY Liu, Y Gao, XY Kui, XS Liu, Y Zhang, Y Zhang… - 2022 - researchsquare.com
Background The purpose of this study was to determine the expression and function of
heterogeneous nuclear ribonucleoprotein R (HNRNPR) in esophageal carcinoma (ESCA) …