[HTML][HTML] Modulation of TLR/NF-κB/NLRP signaling by bioactive phytocompounds: A promising strategy to augment cancer chemotherapy and immunotherapy

S Fakhri, SZ Moradi, A Yarmohammadi… - Frontiers in …, 2022 - frontiersin.org
Background Tumors often progress to a more aggressive phenotype to resist drugs. Multiple
dysregulated pathways are behind this tumor behavior which is known as cancer …

[HTML][HTML] Anticancer Potential of Flavonoids: An Overview with an Emphasis on Tangeretin

FCF de Luna, WAS Ferreira, SMM Casseb… - Pharmaceuticals, 2023 - mdpi.com
Natural compounds with pharmacological activity, flavonoids have been the subject of an
exponential increase in studies in the field of scientific research focused on therapeutic …

[HTML][HTML] Kaempferol and Fisetin-Related Signaling Pathways Induce Apoptosis in Head and Neck Cancer Cells

R Kubina, K Krzykawski, A Dziedzic, A Kabała-Dzik - Cells, 2023 - mdpi.com
Despite the relative effectiveness of standard cancer treatment strategies, head and neck
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …

Dietary flavonoid carvacrol triggers the apoptosis of human breast cancer MCF-7 cells via the p53/Bax/Bcl-2 axis

A Moradipour, H Dariushnejad, C Ahmadizadeh… - Medical Oncology, 2022 - Springer
Recently, numerous studies have shown that natural compounds such as carvacrol can be
used as therapeutic agents for medicinal purposes. Although carvacrol was found to …

[HTML][HTML] Regulatory activities of Warbugia ugandensis ethanolic extracts on colorectal cancer-specific genome expression dose-dependently

JM Macharia, RW Mwangi, I Szabó, A Zand… - Biomedicine & …, 2023 - Elsevier
The evaluation of natural biomass sources is a promising strategy in accelerating the
development of novel anti-cancer medications. Our study aimed to evaluate the activity of W …

Anticancer activity of a novel naringin‒dextrin nanoformula: Preparation, characterization, and in vitro induction of apoptosis in human hepatocellular carcinoma cells …

EE Mohamed, A Abdel-Moneim, OM Ahmed… - Journal of Drug Delivery …, 2022 - Elsevier
Dextrin is a polysaccharide but is small and of low complexity. Naringin is a flavonoid widely
known for its pharmacological properties. This study aimed to create a naringin–dextrin …

Identification of a promising hit from a new series of pyrazolo [1, 5-a] pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro …

HR Elgiushy, SH Mohamed, H Taha, H Sawaf… - Bioorganic …, 2022 - Elsevier
A new series of sixteen new 2-arylamino-5, 7-disubstituted-N-aryl-pyrazolo [1, 5-a]
pyrimidine-3-carboxamide derivatives was designed and synthesized. The antitumor …

[HTML][HTML] Identification of epigenetic dysregulation gene markers and immune landscape in kidney renal clear cell carcinoma by comprehensive genomic analysis

L Xie, S Wu, R He, S Li, X Lai, Z Wang - Frontiers in Immunology, 2022 - frontiersin.org
Kidney cancer is one the most lethal cancers of the urinary system, but current treatments
are limited and its prognosis is poor. This study focused on kidney renal clear cell carcinoma …

Examining the mechanisms of huachansu injection on liver cancer through integrated bioinformatics analysis

C Huang, Y Cheng, W Li, Y Huang… - Recent Patents on …, 2023 - ingentaconnect.com
Objective: The objective of this study is to explore the potential anti-liver cancer mechanism
of Huachansu injection through integrated bioinformatics analysis. Methods: Active …

[HTML][HTML] Efficacy of Prunus armenica, Bee venom, and their combinations on p53 and Bcl-2 gene expression in human pancreatic and lung cancer cells

SF Kadasah, AF Alrefaei, HA Ali - Journal of Umm Al-Qura University for …, 2023 - Springer
Malignancies are one of the world's most serious health problems. Pancreatic and lung
cancers are two of the most lethal types of cancer, with 5-year survival rates ranging from 10 …