Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …

Redox balance is essential to maintain the body's normal metabolism. Once disrupted, it
may lead to various chronic diseases, such as diabetes, neurodegenerative diseases …

Sinomenine is a natural compound extracted from the medicinal plant Sinomenium acutum.
Its supplementation has been shown to present benefits in a variety of animal models of …

Sinomenine is an active substance extracted from the traditional Chinese medicine
Sinomenium acutum. Sinomenine has been shown to mediate a wide range of …

Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …

One of the major causes of long-term disability and mortality is ischemic stroke that enjoys
limited treatment approaches. On the one hand, oxidative stress, induced by excessive …

Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to a
significant social burden. East Asian herbal medicine (EAHM) has long been used to treat …

Inflammatory bowel disease (IBD) is a special chronic intestinal inflammatory disease, which
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …

Chronic pain is a disease of long-lasting pain with unpleasant feelings mediated by central
and (or) peripheral sensitization, its duration usually lasts more than 3 months or longer than …

Autoimmune diseases (ADs), with significant effects on morbidity and mortality, are a broad
spectrum of disorders featured by body's immune responses being directed against its own …