Astaxanthin as a potent antioxidant for promoting bone health: an up-to-date review

I Davan, S Fakurazi, E Alias, NI Ibrahim, NM Hwei… - Antioxidants, 2023 - mdpi.com
In recent years, bone loss and its associated diseases have become a significant public
health concern due to increased disability, morbidity, and mortality. Oxidative stress and …

Ablative and immunostimulatory effects of histotripsy ablation in a murine osteosarcoma model

AN Hay, KM Imran, A Hendricks-Wenger, JM Gannon… - Biomedicines, 2023 - mdpi.com
Background: Osteosarcoma (OS) is the most frequently occurring malignant bone tumor in
humans, primarily affecting children and adolescents. Significant advancements in treatment …

Epigenetic changes associated with osteosarcoma: a comprehensive review

L Twenhafel, DA Moreno, T Punt, M Kinney, R Ryznar - Cells, 2023 - mdpi.com
Osteosarcoma is the most common malignant primary bone tumor in children and
adolescents. While clinical outcomes have improved, the 5-year survival rate is only around …

Doxorubicin-induced senescence in normal fibroblasts promotes in vitro tumour cell growth and invasiveness: The role of Quercetin in modulating these processes

E Bientinesi, M Lulli, M Becatti, S Ristori… - Mechanisms of Ageing …, 2022 - Elsevier
Ageing is a complex biological phenomenon representing the major risk factor for
developing age-related diseases, such as cardiovascular pathologies, neurodegenerative …

At‐risk populations for osteosarcoma: the syndromes and beyond

GT Calvert, RL Randall, KB Jones… - Sarcoma, 2012 - Wiley Online Library
Osteosarcoma is the most common primary malignancy of bone. Most cases are sporadic
without a known genetic or environmental cause. Heritable genetic predisposition …

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

JG van Oosterwijk, JK Anninga… - Hematology …, 2013 - hemonc.theclinics.com
Update on Targets and Novel Treatment Options for High-Grade Osteosarcoma and
Chondrosarcoma - Hematology/Oncology Clinics Skip to Main Content Skip to Main Menu …

Endochondral ossification and the evolution of limb proportions

C Rolian - Wiley Interdisciplinary Reviews: Developmental …, 2020 - Wiley Online Library
Mammals have remarkably diverse limb proportions hypothesized to have evolved
adaptively in the context of locomotion and other behaviors. Mechanistically, evolutionary …

LncRNA DDX11-AS1: a novel oncogene in human cancer

Y Feng, M Wu, S Hu, X Peng, F Chen - Human cell, 2020 - Springer
Long noncoding RNA (lncRNA) is a newly identified type of noncoding RNA with a length of
more than 200 nucleotides. The latest research shows that lncRNAs play important roles in …

Molecular pathogenesis and diagnostic, prognostic and predictive molecular markers in sarcoma

A Mariño-Enríquez, JVMG Bovée - Surgical pathology clinics, 2016 - Elsevier
Sarcomas are infrequent mesenchymal neoplasms characterized by notable morphological
and molecular heterogeneity. Molecular studies in sarcoma provide refinements to …

Nanostructured system based on hydroxyapatite and curcumin: A promising candidate for osteosarcoma therapy

JPN Marinho, NP Neme, MJ de Souza Matos… - Ceramics …, 2023 - Elsevier
Osteosarcoma is the most common type of bone cancer. Despite therapeutic progress,
survival rates for metastatic cases or that do not respond well to chemotherapy remain in the …