Single-cell RNA-seq identification of four differentially expressed survival-related genes by a TARGET: osteosarcoma database analysis

M Feleke, W Feng, E Rothzerg… - Experimental …, 2022 - journals.sagepub.com
Osteosarcoma (OS) differentially expressed genes (DEGs) have been predicted using the
data portal of the Therapeutically Applicable Research to Generate Effective Treatments …

[HTML][HTML] Hsa_circ_0032463 acts as the tumor promoter in osteosarcoma by regulating the miR‑330‑3p/PNN axis

G Qin, X Wu - International Journal of Molecular …, 2021 - spandidos-publications.com
Osteosarcoma (OS), also known as bone cancer, is a threat to the lives of millions of
adolescents worldwide. Although dedicated efforts have been invested in reducing the …

[HTML][HTML] Systematic meta-analysis of genetic variants associated with osteosarcoma susceptibility

X Wang, Z Liu - Medicine, 2018 - journals.lww.com
Background: In the past decade, accumulated evidence has suggested that genetic variation
is related to the pathogenesis of osteosarcoma. Although there are a large number of …

[HTML][HTML] Modified nanoparticles as potential agents in bone diseases: Cancer and implant-related complications

KP Steckiewicz, I Inkielewicz-Stepniak - Nanomaterials, 2020 - mdpi.com
Materials sized 1–100 nm are the nanotechnology's field of interest. Because of the unique
properties such as the ability to penetrate biological barriers and a high surface to volume …

Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells

Y Chang, Y Zhao, H Zhan, X Wei, T Liu, B Zheng - Tumor Biology, 2014 - Springer
Cancer stem cells (CSCs) play an important role in drug resistance of tumor and are
responsible for high recurrence rates. Agents that can suppress the proliferation and …

[HTML][HTML] Upregulation of long noncoding RNA Xist promotes proliferation of osteosarcoma by epigenetic silencing of P21

T Xu, W Jiang, L Fan, Q Gao, G Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recent studies show that lncRNAs involve in the initiation and progression of various
cancers including osteosarcoma (OS). IncRNA Xist has been verified as an oncogene in …

[HTML][HTML] Activation of dynamin-related protein 1-dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

JH Yen, HS Huang, CJ Chuang, ST Huang - Journal of Experimental & …, 2019 - Springer
Background Discovering how to regulate mitochondrial function to reduce cancer growth
holds great potential for future cancer therapy development. Here we explore the effects of …

[HTML][HTML] Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity

L Yu, S Liu, C Zhang, B Zhang, BM Simões, R Eyre… - Oncotarget, 2013 - ncbi.nlm.nih.gov
Telomerase is crucial for the maintenance of stem/progenitor cells in adult tissues and is
detected in most malignant cancers, including osteosarcoma. However, the relationship …

Advances in therapy for pediatric sarcomas

A Weiss, J Gill, J Goldberg, J Lagmay… - Current oncology …, 2014 - Springer
Pediatric sarcomas are relatively rare malignancies individually. As a group they are
typically approached with combination chemotherapies in addition to local control …

[HTML][HTML] The potential selective cytotoxicity of poly (L-lactic acid)-based scaffolds functionalized with nanohydroxyapatite and europium (III) ions toward osteosarcoma …

M Sikora, K Marcinkowska, K Marycz, RJ Wiglusz… - Materials, 2019 - mdpi.com
Osteosarcoma (OSA) is malignant bone tumor, occurring in children and adults,
characterized by poor prognosis. Despite advances in chemotherapy and surgical …