Overcoming cancer chemotherapy resistance by the induction of ferroptosis
Y Wang, X Wu, Z Ren, Y Li, W Zou, J Chen… - Drug Resistance …, 2023 - Elsevier
Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …
Role of NRF2 in ovarian cancer
G Tossetta, S Fantone, E Montanari, D Marzioni… - Antioxidants, 2022 - mdpi.com
Among gynaecologic malignancies, ovarian cancer is one of the most dangerous, with a
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
Targeting the NRF2/KEAP1 pathway in cervical and endometrial cancers
G Tossetta, D Marzioni - European Journal of Pharmacology, 2023 - Elsevier
Cervical and endometrial cancers are among the most dangerous gynaecological
malignancies, with high fatality and recurrence rates due to frequent diagnosis at an …
malignancies, with high fatality and recurrence rates due to frequent diagnosis at an …
Cisplatin for cancer therapy and overcoming chemoresistance
Cisplatin spearheads the anticancer chemotherapeutics in present-day use although acute
toxicity is its primary impediment factor. Among a plethora of experimental medications, a …
toxicity is its primary impediment factor. Among a plethora of experimental medications, a …
Cervical cancer heterogeneity: a constant battle against viruses and drugs
Q Sun, L Wang, C Zhang, Z Hong, Z Han - Biomarker Research, 2022 - Springer
Cervical cancer is the first identified human papillomavirus (HPV) associated cancer and the
most promising malignancy to be eliminated. However, the ever-changing virus subtypes …
most promising malignancy to be eliminated. However, the ever-changing virus subtypes …
linc00958/miR-185-5p/RSF-1 modulates cisplatin resistance and angiogenesis through AKT1/GSK3β/VEGFA pathway in cervical cancer
J Tian, L Cheng, E Kong, W Gu, Y Jiang, Q Hao… - Reproductive Biology …, 2022 - Springer
Background Chemoresistance is one of the major obstacles that lead to poor prognosis in
cervical cancer. linc00958 was reported to be an oncogene in cervical cancer. However, its …
cervical cancer. linc00958 was reported to be an oncogene in cervical cancer. However, its …
Evaluation of long non-coding RNA (LncRNA) in the pathogenesis of chemotherapy resistance in cervical cancer: diagnostic and prognostic approach
N Modabber, SS Mahboub, S Khoshravesh… - Molecular …, 2023 - Springer
Cervical cancer (CC), caused by human papillomavirus (HPV), is a leading cause of female
malignancies worldwide. Therefore, understanding the underlying mechanisms of CC …
malignancies worldwide. Therefore, understanding the underlying mechanisms of CC …
Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1
S Deng, L Qian, L Liu, H Liu, Z Xu, Y Liu… - Cancer …, 2023 - Wiley Online Library
Cervical squamous cell carcinoma (CSCC) is one of the leading causes of cancer death in
women worldwide. Patients with advanced cervical carcinoma always have a poor …
women worldwide. Patients with advanced cervical carcinoma always have a poor …
Downregulation of miR-21 as a promising strategy to overcome drug resistance in cancer
Despite tremendous achievements in the field of targeted cancer therapy, chemotherapy is
still the main treatment option, which is challenged by acquired drug resistance. Various …
still the main treatment option, which is challenged by acquired drug resistance. Various …