Hydroxylation decoration patterns of flavonoids in horticultural crops: Chemistry, bioactivity, and biosynthesis

Y Liu, J Qian, J Li, M Xing, D Grierson… - Horticulture …, 2022 - academic.oup.com
Flavonoids are the most widespread polyphenolic compounds and are important dietary
constituents present in horticultural crops such as fruits, vegetables, and tea. Natural …

[HTML][HTML] The current developments in medicinal plant genomics enabled the diversification of secondary metabolites' biosynthesis

MM Alami, Z Ouyang, Y Zhang, S Shu, G Yang… - International journal of …, 2022 - mdpi.com
Medicinal plants produce important substrates for their adaptation and defenses against
environmental factors and, at the same time, are used for traditional medicine and industrial …

[HTML][HTML] SMARTdenovo: a de novo assembler using long noisy reads

H Liu, S Wu, A Li, J Ruan - Gigabyte, 2021 - ncbi.nlm.nih.gov
Long-read single-molecule sequencing has revolutionized de novo genome assembly and
enabled the automated reconstruction of reference-quality genomes. It has also been widely …

High efficient production of plant flavonoids by microbial cell factories: Challenges and opportunities

J Sun, W Sun, G Zhang, B Lv, C Li - Metabolic engineering, 2022 - Elsevier
Plant flavonoids are secondary metabolites containing a benzo-γ-pyrone structure, which
are widely present in plants and have a variety of physiological and pharmacological …

Multiomics analyses of two Leonurus species illuminate leonurine biosynthesis and its evolution

P Li, MX Yan, P Liu, DJ Yang, ZK He, Y Gao, Y Jiang… - Molecular Plant, 2024 - cell.com
The Lamiaceae family is renowned for its terpenoid-based medicinal components, but
Leonurus, which has traditional medicinal uses, stands out for its alkaloid-rich composition …

[HTML][HTML] Specific Flavonoids and Their Biosynthetic Pathway in Scutellaria baicalensis

T Pei, M Yan, Y Huang, Y Wei, C Martin… - Frontiers in plant …, 2022 - frontiersin.org
Scutellaria baicalensis, is one of the most traditional medicinal plants in the Lamiaceae
family, and has been widely used to treat liver and lung complaints and as a complementary …

[HTML][HTML] Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae

Y Zhang, J Gao, L Ma, L Tu, T Hu, X Wu, P Su… - Nature …, 2023 - nature.com
Triptolide is a valuable multipotent antitumor diterpenoid in Tripterygium wilfordii, and its C-
14 hydroxyl group is often selected for modification to enhance both the bioavailability and …

[HTML][HTML] Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia

J Hu, S Qiu, F Wang, Q Li, CL Xiang, P Di, Z Wu… - Nature …, 2023 - nature.com
Abstract The genus Salvia L.(Lamiaceae) comprises myriad distinct medicinal herbs, with
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …

[HTML][HTML] Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory

AE Bryson, ER Lanier, KH Lau, JP Hamilton… - Nature …, 2023 - nature.com
The spatial organization of genes within plant genomes can drive evolution of specialized
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …

The chromosome‐scale assembly of the Salvia rosmarinus genome provides insight into carnosic acid biosynthesis

D Han, W Li, Z Hou, C Lin, Y Xie, X Zhou… - The Plant …, 2023 - Wiley Online Library
Rosemary (Salvia rosmarinus) is considered a sacred plant because of its special fragrance
and is commonly used in cooking and traditional medicine. Here, we report a high‐quality …