The success of hematopoietic stem cell transplantation (HSCT) lies with the ability of the
engrafting immune system to remove residual leukemia cells via a graft-versus-leukemia …

Pain and stress have been shown to induce significant physiological and behavioral
reactions in newborn infants, even in those born prematurely. Infants who are born …

The immune reactivity of allogeneic lymphocytes plays a major role in the control of
leukemia after bone marrow transplantation. In patients with recurrent leukemia after marrow …

In allogeneic bone marrow transplantation (allo-BMT), donor lymphocytes play a central
therapeutic role in both graft-versus-leukemia (GvL) and immune reconstitution. However …

Summary Reactivation of Epstein-Barr virus (EBV) after bone-marrow transplantation leads
in many cases to lymphoproliferative disease that responds poorly to standard therapy and …

Although the immune system has long been implicated in the control of cancer, evidence for
specific and efficacious immune responses in human cancer has been lacking. In the case …

Infusions of large numbers (> 10 (8)/kg) of donor leukocytes can induce remissions in
patients with chronic myeloid leukemia (CML) who relapse after marrow transplantation. We …

The presence of a graft-versus-tumor effect has been well established in leukemia but not in
multiple myeloma. A 40-year-old patient with myeloma refractory to standard chemotherapy …

FLT3 mutations, either internal tandem duplications (ITDs) or aspartate residue 835 (D835)
point mutations, are present in approximately one third of patients with acute myeloid …

Purpose We recently reported that children with acute leukemias who show increasing
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …