Objective Stereoelectroencephalography (SEEG) is the reference method in the presurgical
exploration of drug‐resistant focal epilepsy. However, prognosticating surgery on an …

The neuronal circuit disturbances that drive inter-ictal and ictal epileptiform discharges
remain elusive. Using a combination of extra-operative macro-electrode and micro-electrode …

An estimated 70 million people are affected by epilepsy worldwide, 1 and of these patients,
more than 30% are thought to have intractable and drug-resistant disease according to the …

Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …

High frequency oscillations are a promising biomarker of outcome in intractable epilepsy.
Prior high frequency oscillation work focused on counting high frequency oscillations on …

How responsive neurostimulation (RNS) decreases seizure frequency is unclear.
Stimulation may alter epileptic networks during inter‐ictal epochs. Definitions of the epileptic …

In medication-resistant epilepsy, the goal of epilepsy surgery is to make a patient seizure
free with a resection/ablation that is as small as possible to minimize morbidity. The standard …

Spontaneous inter-ictal epileptiform spikes (ie spikes) were first recognized nearly a century
ago in extracellular recordings from animals exposed to chemoconvulsants and in the EEG …

Every year, tens of millions of people around the world suffer from epilepsy. 1, 2 This
common neurological disorder affects people of all ages and is characterized by chronic …