The m6A eraser FTO suppresses ferroptosis via mediating ACSL4 in LPS-induced macrophage inflammation

Y Zhao, W Ding, Y Cai, Q Li, W Zhang, Y Bai… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Acute lung injury (ALI) is a serious disorder characterized by the release of pro-inflammatory
cytokines and cascade activation of macrophages. Ferroptosis, a form of iron-dependent cell …

The suppression of FSP1 expression via NRF2 promotes ferroptosis induced by reactive oxygen species in vascular smooth muscle cells

Z Xie, J Guo, Y Deng, P Yu, C Zhi, Y He, X Tan, P Li… - Process …, 2024 - Elsevier
Death of vascular smooth muscle cells (VSMC) induced by reactive oxygen species (ROS)
may occur as ferroptosis, contributing to atherosclerotic plaque instability and rupture …

TRPV1 Regulates Proinflammatory Properties of M1 Macrophages in Periodontitis Via NRF2

Y Li, X Guo, P Zhan, S Huang, J Chen, Y Zhou, W Jiang… - Inflammation, 2024 - Springer
Periodontitis, characterized by progressive alveolar bone destruction, leads to the loss of
attachment and stability of the affected teeth. Macrophages, especially the proinflammatory …

Deferasirox Causes Leukaemia Cell Death through Nrf2-Induced Ferroptosis

WY Hsu, LT Wang, PC Lin, YM Liao, SH Hsu, SS Chiou - Antioxidants, 2024 - mdpi.com
Acute lymphoblastic leukaemia (ALL) is the most prevalent cancer in children, and
excessive iron buildup resulting from blood transfusions and chemotherapy potentially has a …

[HTML][HTML] Exploring the molecular mechanisms of ferroptosis-related genes in periodontitis: a multi-dataset analysis

J Chen, L Ou, W Liu, F Gao - BMC Oral Health, 2024 - Springer
Purpose This study aims to elucidate the biological functions of ferroptosis-related genes in
periodontitis, along with their correlation to tumor microenvironment (TME) features such as …

[PDF][PDF] Assessment of Blood-Derived Macrophages from Individuals with Crohn's Disease: Potential Role of Diet and Selenium

JA Sousa - Assessment, 2024 - prism.ucalgary.ca
There is growing evidence of the role of diet in modulating immune function in inflammatory
conditions such as inflammatory bowel disease (IBD). Specifically, there are alterations in …

Protective role of curcumin in high glucose-induced osteoblast dysfunctions via Nrf2 activation and ROS/JNK signaling inhibition

Q Zhang, M Yu, F Teng - 2024 - techrxiv.org
Aim: High glucose (HG) impairs the viability and function of osteoblast, thus causing bone
metabolism disorder and osteoporosis. Curcumin is a polyphenolic phytochemical derived …