[HTML][HTML] The landscape of implantation and placentation: deciphering the function of dynamic RNA methylation at the maternal-fetal interface
S Wu, H Xie, Y Su, X Jia, Y Mi, Y Jia… - Frontiers in …, 2023 - frontiersin.org
The maternal-fetal interface is defined as the interface between maternal tissue and sections
of the fetus in close contact. RNA methylation modifications are the most frequent kind of …
of the fetus in close contact. RNA methylation modifications are the most frequent kind of …
Exploring the role of m6A modification in the great obstetrical syndromes
J Ning, J Yan, H Yang - The Journal of Maternal-Fetal & Neonatal …, 2023 - Taylor & Francis
Abstract Background N6-methyladenosine (m6A) is one of the predominant RNA epigenetic
modifications that modify RNAs reversibly and dynamically by “writers”(methyltransferase),“ …
modifications that modify RNAs reversibly and dynamically by “writers”(methyltransferase),“ …
METTL3 promotes trophoblast ferroptosis in preeclampsia by stabilizing the ACSL4 m6A modification
Y Wang, G Zhang, Y Gao, X Zhang, H Qi - Experimental Cell Research, 2024 - Elsevier
This study aims to explore the role of methyltransferase-like 3 (METTL3) modulation of
ferroptosis in the pathogenesis of trophoblast-mediated preeclampsia. The expression of …
ferroptosis in the pathogenesis of trophoblast-mediated preeclampsia. The expression of …
[HTML][HTML] METTL3-mediated lncRNA HOXD-AS1 stability regulates inflammation, and the migration and invasion of trophoblast cells via the miR-135a/β-TRCP axis
L Wang, L Shi, B Zhou, L Hong, H Gong… - Non-coding RNA Research, 2024 - Elsevier
Background Preeclampsia (PE) is a serious pregnancy-specific syndrome associated with
the inadequate invasion of trophoblast cells and inflammation of the uterus. A previous study …
the inadequate invasion of trophoblast cells and inflammation of the uterus. A previous study …
USP18 Stabilized FTO Protein to Activate Mitophagy in Ischemic Stroke Through Repressing m6A Modification of SIRT6
M Song, F Yi, F Zeng, L Zheng, L Huang, X Sun… - Molecular …, 2024 - Springer
Ischemic stroke (IS) is a dangerous cerebrovascular disorder with a significant incidence
and death rate. Ubiquitin-specific peptidase 18 (USP18) has been proven to mitigate …
and death rate. Ubiquitin-specific peptidase 18 (USP18) has been proven to mitigate …
CPEB2 inhibits preeclampsia progression by regulating SSTR3 translation through polyadenylation
Y Zhao, L Zhang, J Yang, C Li, P Li - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Aims Trophoblast cell dysfunction is one of the important factors leading to preeclampsia
(PE). Cytoplasmic polyadenylation element-binding 2 (CPEB2) has been found to be …
(PE). Cytoplasmic polyadenylation element-binding 2 (CPEB2) has been found to be …
[HTML][HTML] Downregulation of RNA binding protein 47 predicts low survival in patients and promotes the development of renal cell malignancies through RNA stability …
C Wang, W Li, X Meng, H Yuan, T Yu, W Yang… - Molecular …, 2023 - Springer
RNA binding proteins (RBPs) are crucial for cell function, tissue growth, and disease
development in disease or normal physiological processes. RNA binding motif protein 47 …
development in disease or normal physiological processes. RNA binding motif protein 47 …
[HTML][HTML] Overexpression of RBM15 modulated the effect of trophoblast cells by promoting the binding ability between YTHDF2 and the CD82 3′ UTR to decrease the …
G You, Z Li, L Li, C Xu - Heliyon, 2024 - cell.com
Abstracts Background Pre-eclampsia (PE) is a syndrome with no specific pathological
mechanism and is specific to pregnancy. The combined analysis of proteomics and …
mechanism and is specific to pregnancy. The combined analysis of proteomics and …
[HTML][HTML] Demethylase FTO inhibits the occurrence and development of triple-negative breast cancer by blocking m 6A-dependent miR-17-5p maturation-induced …
J Ni, X Lu, X Gao, C Jin, J Mao - Acta Biochimica et Biophysica …, 2024 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is a subtype of breast cancer, and its mechanisms of
occurrence and development remain unclear. In this study, we aim to investigate the role …
occurrence and development remain unclear. In this study, we aim to investigate the role …