The major histocompatibility complex (MHC) is a gene dense region found in all jawed
vertebrates examined to date. The MHC contains a high percentage of immune genes, in …

Abstract Background Chitinases (EC. 3.2. 1.14) hydrolyze the β-1, 4-linkages in chitin, an
abundant N-acetyl-β-D-glucosamine polysaccharide that is a structural component of …

Nearly all genes presently mapped to chicken chromosome 16 (GGA 16) have either a
demonstrated role in immune responses or are considered to serve in immunity by reason of …

Abstract HLA class I and NK receptors are encoded within dense clusters of immune loci.
The MHC, at 6p21. 3, and the complex containing the KIR loci, at 19q13. 4, both feature …

Xenopus laevis is the model of choice for evolutionary, comparative, and developmental
studies of immunity, and invaluable research tools including MHC‐defined clones, inbred …

MHC gene organization (size, complexity, gene order) differs markedly among different
species, and yet all nonmammalian vertebrates examined to date have a true" class I region" …

This review is a comprehensive introduction to the effects of poultry exposure to the toxic
and carcinogenic mycotoxin aflatoxin B1 (AFB1). The relationship between AFB1 sensitivity …

Given large sample sizes, whole genome screens are now able to identify even quite
modest contributions of common human genetic variation to disease. These approaches …

In comparison with the major histocompatibility complexes (MHCs) of typical mammals, the
chicken MHC is simple and compact with a single dominantly expressed class I molecule …

Few studies have yet addressed the functional aspects of MHC molecules in fish. To lay the
foundation for this, we evaluated the association between disease resistance and MHC …