Comparative genomics of major histocompatibility complexes
J Kelley, L Walter, J Trowsdale - Immunogenetics, 2005 - Springer
The major histocompatibility complex (MHC) is a gene dense region found in all jawed
vertebrates examined to date. The MHC contains a high percentage of immune genes, in …
vertebrates examined to date. The MHC contains a high percentage of immune genes, in …
Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family
JD Funkhouser, NN Aronson - BMC evolutionary biology, 2007 - Springer
Abstract Background Chitinases (EC. 3.2. 1.14) hydrolyze the β-1, 4-linkages in chitin, an
abundant N-acetyl-β-D-glucosamine polysaccharide that is a structural component of …
abundant N-acetyl-β-D-glucosamine polysaccharide that is a structural component of …
[HTML][HTML] Brief review of the chicken major histocompatibility complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance
MM Miller, RL Taylor Jr - Poultry Science, 2016 - Elsevier
Nearly all genes presently mapped to chicken chromosome 16 (GGA 16) have either a
demonstrated role in immune responses or are considered to serve in immunity by reason of …
demonstrated role in immune responses or are considered to serve in immunity by reason of …
Genetic and functional relationships between MHC and NK receptor genes
J Trowsdale - Immunity, 2001 - cell.com
Abstract HLA class I and NK receptors are encoded within dense clusters of immune loci.
The MHC, at 6p21. 3, and the complex containing the KIR loci, at 19q13. 4, both feature …
The MHC, at 6p21. 3, and the complex containing the KIR loci, at 19q13. 4, both feature …
Comparative and developmental study of the immune system in Xenopus
J Robert, Y Ohta - Developmental Dynamics, 2009 - Wiley Online Library
Xenopus laevis is the model of choice for evolutionary, comparative, and developmental
studies of immunity, and invaluable research tools including MHC‐defined clones, inbred …
studies of immunity, and invaluable research tools including MHC‐defined clones, inbred …
Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system
MF Flajnik, M Kasahara - Immunity, 2001 - cell.com
MHC gene organization (size, complexity, gene order) differs markedly among different
species, and yet all nonmammalian vertebrates examined to date have a true" class I region" …
species, and yet all nonmammalian vertebrates examined to date have a true" class I region" …
Aflatoxicosis: Lessons from Toxicity and Responses to Aflatoxin B1 in Poultry
This review is a comprehensive introduction to the effects of poultry exposure to the toxic
and carcinogenic mycotoxin aflatoxin B1 (AFB1). The relationship between AFB1 sensitivity …
and carcinogenic mycotoxin aflatoxin B1 (AFB1). The relationship between AFB1 sensitivity …
The MHC, disease and selection
J Trowsdale - Immunology letters, 2011 - Elsevier
Given large sample sizes, whole genome screens are now able to identify even quite
modest contributions of common human genetic variation to disease. These approaches …
modest contributions of common human genetic variation to disease. These approaches …
Generalists and specialists: a new view of how MHC class I molecules fight infectious pathogens
J Kaufman - Trends in Immunology, 2018 - cell.com
In comparison with the major histocompatibility complexes (MHCs) of typical mammals, the
chicken MHC is simple and compact with a single dominantly expressed class I molecule …
chicken MHC is simple and compact with a single dominantly expressed class I molecule …
MHC polymorphism and disease resistance in Atlantic salmon (Salmo salar); facing pathogens with single expressed major histocompatibility class I and class II loci
U Grimholt, S Larsen, R Nordmo, P Midtlyng… - Immunogenetics, 2003 - Springer
Few studies have yet addressed the functional aspects of MHC molecules in fish. To lay the
foundation for this, we evaluated the association between disease resistance and MHC …
foundation for this, we evaluated the association between disease resistance and MHC …