Bioengineering extracellular vesicle cargo for optimal therapeutic efficiency

CA René, RJ Parks - Molecular Therapy Methods & Clinical Development, 2024 - cell.com
Extracellular vesicles (EVs) have the innate ability to carry proteins, lipids, and nucleic acids
between cells, and thus these vesicles have gained much attention as potential therapeutic …

Mesenchymal Stem Cells in the Treatment of COVID-19

BC Guo, KH Wu, CY Chen, WY Lin, YJ Chang… - International Journal of …, 2023 - mdpi.com
Since the emergence of the coronavirus disease 2019 (COVID-19) pandemic, many lives
have been tragically lost to severe infections. The COVID-19 impact extends beyond the …

[HTML][HTML] Immunomodulation of adipose-derived mesenchymal stem cells on peripheral blood mononuclear cells in colorectal cancer patients with COVID-19

JF Wang, XX Yang, J Zhang, Y Zheng… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Accumulating evidence has shown that adipose tissue-derived
mesenchymal stem cells (ADSCs) are an effective therapeutic approach for managing …

MSC-Based Cell Therapy for COVID-19-Associated ARDS and Classical ARDS: Comparative Perspectives

DJ Weiss, S Rolandsson Enes - Current Stem Cell Reports, 2024 - Springer
Abstract Purpose of Review Despite no general conclusions regarding the therapeutic effect
of MSCs on virus-induced acute lung injury in pre-clinical studies, a significant number of …

Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium

SY Lee - bioRxiv, 2024 - biorxiv.org
Dysfunction of the retinal pigment epithelium (RPE) is a common shared pathology in major
degenerative retinal diseases despite variations in the primary etiologies of each disease …

Adjunctive treatment of sepsis with mesenchymal stem cell-derived extracellular vesicles: a systemic review and meta-analysis of pre-clinical studies

A Charoensappakit, K Sae‑khow, P Rattanaliam… - 2024 - researchsquare.com
Background: Multiple preclinical studies have reported a beneficial effect of extracellular
vesicles (EVs), especially mesenchymal stem cell-derived EVs (MSC-EVs), in the treatment …

[PDF][PDF] WJGO

HH Wang, L Li, PD Terry, WJ Kou, Y Zhang… - …, 2023 - pdfs.semanticscholar.org
Gastric cancer is one of the most common digestive system tumors in China, and locally
advanced gastric cancer (LAGC) accounts for a high proportion of newly diagnosed cases …