Glial cells in Alzheimer's disease: From neuropathological changes to therapeutic implications
MS Uddin, LW Lim - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …
progressively worsens over time. Although there has been increasing research interest in …
[HTML][HTML] Alzheimer's disease: treatment strategies and their limitations
Alzheimer's disease (AD) is the most frequent case of neurodegenerative disease and is
becoming a major public health problem all over the world. Many therapeutic strategies …
becoming a major public health problem all over the world. Many therapeutic strategies …
[HTML][HTML] Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment
Q Yang, X Wei, B Deng, Z Chang, D Jin, Y Huang… - Neurobiology of …, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …
disorders caused by the structural changes of cerebral microvessels, including the small …
Intrinsically disordered proteins and proteins with intrinsically disordered regions in neurodegenerative diseases
O Coskuner-Weber, O Mirzanli, VN Uversky - Biophysical Reviews, 2022 - Springer
Many different intrinsically disordered proteins and proteins with intrinsically disordered
regions are associated with neurodegenerative diseases. These types of proteins including …
regions are associated with neurodegenerative diseases. These types of proteins including …
Role of melatonin in Alzheimer's disease: from preclinical studies to novel melatonin-based therapies
Melatonin and novel melatonin-based therapies such as melatonin-containing hybrid
molecules, melatonin analogues, and melatonin derivatives have been investigated as …
molecules, melatonin analogues, and melatonin derivatives have been investigated as …
[HTML][HTML] Berberine improves cognitive impairment by simultaneously impacting cerebral blood flow and β-amyloid accumulation in an APP/tau/PS1 mouse model of …
C Ye, Y Liang, Y Chen, Y Xiong, Y She, X Zhong… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is accompanied by β-amyloid (Aβ), neurofibrillary tangles, and
neuron cell death, and is one of the most commonly occurring diseases among the elderly …
neuron cell death, and is one of the most commonly occurring diseases among the elderly …
[HTML][HTML] Sex differences between neuronal loss and the early onset of amyloid deposits and behavioral consequences in 5xFAD transgenic mouse as a model for …
A promising direction in the research on Alzheimer's Disease (AD) is the identification of
biomarkers that better inform the disease progression of AD. However, the performance of …
biomarkers that better inform the disease progression of AD. However, the performance of …
Exploring the multifunctional role of melatonin in regulating autophagy and sleep to mitigate Alzheimer's disease neuropathology
Melatonin (MLT) is a neurohormone that is regulated by the circadian clock and plays
multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's …
multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's …
[HTML][HTML] The monkey head mushroom and memory enhancement in Alzheimer's disease
Yanshree, WS Yu, ML Fung, CW Lee, LW Lim… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder, and no effective treatments are
available to treat this disorder. Therefore, researchers have been investigating Hericium …
available to treat this disorder. Therefore, researchers have been investigating Hericium …
[HTML][HTML] The role of butyrylcholinesterase and iron in the regulation of cholinergic network and cognitive dysfunction in Alzheimer's disease pathogenesis
J Jasiecki, M Targońska, B Wasąg - International Journal of Molecular …, 2021 - mdpi.com
Alzheimer's disease (AD), the most common form of dementia in elderly individuals, is
marked by progressive neuron loss. Despite more than 100 years of research on AD, there …
marked by progressive neuron loss. Despite more than 100 years of research on AD, there …