[HTML][HTML] Implications of testicular ACE2 and the renin–angiotensin system for SARS-CoV-2 on testis function

RC Edenfield, CA Easley IV - Nature Reviews Urology, 2022 - nature.com
Although many studies have focused on SARS-CoV-2 infection in the lungs, comparatively
little is known about the potential effects of the virus on male fertility. SARS-CoV-2 infection …

[HTML][HTML] Zika virus

S Masmejan, D Musso, M Vouga, L Pomar… - Pathogens, 2020 - mdpi.com
Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause
of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations …

[HTML][HTML] Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation

W Yang, LB Liu, FL Liu, YH Wu, ZD Zhen… - Nature …, 2023 - nature.com
Zika virus (ZIKV) is a potential threat to male reproductive health but the mechanisms
underlying its influence on testes during ZIKV infection remain obscure. To address this …

[HTML][HTML] Update on known and emergent viruses affecting human male genital tract and fertility

S Dabizzi, M Maggi, MG Torcia - Basic and Clinical Andrology, 2024 - Springer
Many viruses infect the male genital tract with harmful consequences at individual and
population levels. In fact, viral infections may induce damage to different organs of the male …

[HTML][HTML] Favipiravir Suppresses Zika Virus (ZIKV) through Activity as a Mutagen

EJ Franco, E Cella, X Tao, KC Hanrahan, T Azarian… - Microorganisms, 2023 - mdpi.com
In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV)
suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC …

[HTML][HTML] Human seminal virome: a panel based on recent literature

BHDR de Albuquerque, MTFC de Oliveira… - Basic and Clinical …, 2022 - Springer
Background The seminal virome and its implications for fertility remain poorly understood.
To date, there are no defined panels for the detection of viruses of clinical interest in seminal …

Review of Sertoli cell dysfunction caused by COVID-19 that could affect male fertility

AN Tabar, K Sojoudi, H Henduei, H Azizi - Zygote, 2022 - cambridge.org
Spermatogenesis is a complex and elaborate differentiation process and is vital for male
fertility. Sertoli cells play a major role in fertility and induce spermatogenesis by protecting …

Molecular changes in the testes of COVID-19 patients

G Demyashkin, E Kogan, D Boldyrev… - Journal of …, 2024 - Taylor & Francis
After the sudden outbreak of the COVID-19 pandemic, scientists and clinicians around the
world have significantly expanded understanding of the pathogenesis of the disease as well …

[HTML][HTML] Favipiravir Inhibits Zika Virus (ZIKV) Replication in HeLa Cells by Altering Viral Infectivity

EJ Franco, KC Hanrahan, AN Brown - Microorganisms, 2023 - mdpi.com
This study aims to evaluate the antiviral potential of the nucleoside analogue favipiravir
(FAV) against ZIKV, an arbovirus for which there are no approved antiviral therapies, in three …

[HTML][HTML] Zika RNA and flavivirus-like antigens in the sperm cells of symptomatic and asymptomatic subjects

H Vanegas, F González, Y Reyes, E Centeno… - Viruses, 2021 - mdpi.com
Zika virus (ZIKV) RNA has been found to remain in human semen for up to one year after
infection, but the presence of Flavivirus antigens in the different compartments of semen has …