Large-vessel vasculitis
D Pugh, M Karabayas, N Basu, MC Cid… - Nature Reviews …, 2021 - nature.com
Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …
Antibody–drug conjugates for cancer therapy
Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …
monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the …
The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics
The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
Colyliform Crystalline 2D Covalent Organic Frameworks (COFs) with Quasi‐3D Topologies for Rapid I2 Adsorption
X Guo, Y Li, M Zhang, K Cao, Y Tian… - Angewandte Chemie …, 2020 - Wiley Online Library
Abstract Constructing three‐dimensional (3D) structural characteristics on two‐dimensional
(2D) covalent organic frameworks (COFs) is a good approach to effectively improve the …
(2D) covalent organic frameworks (COFs) is a good approach to effectively improve the …
Lanthanide porphyrinoids as molecular theranostics
In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as
theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow …
theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow …
Radiochemistry for positron emission tomography
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …
oncology treatments, emerges in the current management of cancer. A growing number of …
Nanoprobe-based molecular imaging for tumor stratification
X Ma, M Mao, J He, C Liang, HY Xie - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …
stratification has been attracting increasing attention for accurately distinguishing between …
Deferoxamine B: A natural, excellent and versatile metal chelator
D Bellotti, M Remelli - Molecules, 2021 - mdpi.com
Deferoxamine B is an outstanding molecule which has been widely studied in the past
decade for its ability to bind iron and many other metal ions. The versatility of this metal …
decade for its ability to bind iron and many other metal ions. The versatility of this metal …
Molecular and functional imaging in cancer-targeted therapy: current applications and future directions
JW Bai, SQ Qiu, GJ Zhang - Signal Transduction and Targeted Therapy, 2023 - nature.com
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …