[HTML][HTML] Bacterial biofilm formation on biomaterials and approaches to its treatment and prevention
P Li, R Yin, J Cheng, J Lin - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial biofilms can cause widespread infection. In addition to causing urinary tract
infections and pulmonary infections in patients with cystic fibrosis, biofilms can help …
infections and pulmonary infections in patients with cystic fibrosis, biofilms can help …
[HTML][HTML] Update on the discovery of efflux pump inhibitors against critical priority Gram-negative bacteria
N Compagne, A Vieira Da Cruz, RT Müller… - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance (AMR) has become a major problem in public health leading to an
estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and …
estimated 4.95 million deaths in 2019. The selective pressure caused by the massive and …
[HTML][HTML] Efflux pump inhibitors in controlling antibiotic resistance: outlook under a heavy metal contamination context
Multi-drug resistance to antibiotics represents a growing challenge in treating infectious
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …
[HTML][HTML] Repurposing antidepressants and phenothiazine antipsychotics as efflux pump inhibitors in cancer and infectious diseases
B Rácz, G Spengler - Antibiotics, 2023 - mdpi.com
Multidrug resistance (MDR) is a major obstacle in the therapy of infectious diseases and
cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) …
cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) …
[PDF][PDF] Exploring Mangifera indica (Anacardiaceae) leaf and bark methanol extracts as potential adjuvant therapy in the management of multidrug-resistant …
B Ekamgue, AT Mbaveng, AJ Seukep… - Invest Med Chem …, 2023 - investchempharma.com
Background: After several decades of antibiotic use, pathogenic bacteria have reached
alarming levels of resistance. Staphylococcus aureus is the most common cause of …
alarming levels of resistance. Staphylococcus aureus is the most common cause of …
Harnessing the potential of bimetallic nanoparticles: Exploring a novel approach to address antimicrobial resistance
S Bharti - World Journal of Microbiology and Biotechnology, 2024 - Springer
The growing global importance of antimicrobial resistance (AMR) in public health has
prompted the creation of innovative approaches to combating the issue. In this study, the …
prompted the creation of innovative approaches to combating the issue. In this study, the …
Study on the inhibitory effect of quercetin combined with gentamicin on the formation of Pseudomonas aeruginosa and its bioenvelope
S Luo, X Kang, X Luo, C Li, G Wang - Microbial Pathogenesis, 2023 - Elsevier
Objective The potential effects of quercetin and gentamicin combination on the bacteriostatic
activity and biofilm formation of Pseudomonas aeruginosa (PA) were examined, and the …
activity and biofilm formation of Pseudomonas aeruginosa (PA) were examined, and the …
[PDF][PDF] Psidium guajava (Myrtaceae) re-sensitizes multidrug-resistant Pseudomonas aeruginosa over-expressing MexAB-OprM efflux pumps to commonly prescribed …
RS Tiotsop, AT Mbaveng, AJ Seukep… - Invest Med Chem …, 2023 - researchgate.net
Background: Pseudomonas aeruginosa is a critical-class priority pathogen showing high
resistance to almost all classes of conventional antibiotics. As a result, discovering new …
resistance to almost all classes of conventional antibiotics. As a result, discovering new …
[HTML][HTML] Advances in the Discovery of Efflux Pump Inhibitors as Novel Potentiators to Control Antimicrobial-Resistant Pathogens
The excessive use of antibiotics has led to the emergence of multidrug-resistant (MDR)
pathogens in clinical settings and food-producing animals, posing significant challenges to …
pathogens in clinical settings and food-producing animals, posing significant challenges to …
Amphiphilic peptide Mastoparan‐B induces conformational changes within the AdeB efflux pump, down‐regulates adeB gene expression, and restores antibiotic susceptibility in …
Abstract Mastoparan B (MP‐B) is an amphiphilic peptide with a potent antimicrobial activity
against most Gram‐negative bacteria. However, there is little information available on the …
against most Gram‐negative bacteria. However, there is little information available on the …