Deployment of machine learning algorithms to predict sepsis: systematic review and application of the SALIENT clinical AI implementation framework

AH van der Vegt, IA Scott, K Dermawan… - Journal of the …, 2023 - academic.oup.com
Objective To retrieve and appraise studies of deployed artificial intelligence (AI)-based
sepsis prediction algorithms using systematic methods, identify implementation barriers …

Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

[HTML][HTML] Systemic inflammatory response syndrome

RK Chakraborty, B Burns - 2019 - europepmc.org
Systemic Inflammatory Response Syndrome - Abstract - Europe PMC Sign in | Create an
account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk …

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

J Ma, K Wei, J Liu, K Tang, H Zhang, L Zhu… - Nature …, 2020 - nature.com
Our current understanding of how sugar metabolism affects inflammatory pathways in
macrophages is incomplete. Here, we show that glycogen metabolism is an important event …

An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial

RS Nannan Panday, EMJ Lammers, N Alam… - Critical Care, 2019 - Springer
Background Sepsis remains one of the most important causes of morbidity and mortality
worldwide. In approximately 30–50% of cases of suspected sepsis, no pathogen is isolated …

Frailty and associated outcomes and resource utilization among older ICU patients with suspected infection

SM Fernando, DI McIsaac, JJ Perry… - Critical Care …, 2019 - journals.lww.com
Objectives: Suspected infection and sepsis are common conditions seen among older ICU
patients. Frailty has prognostic importance among critically ill patients, but its impact on …

[HTML][HTML] β-glucan-coupled superparamagnetic iron oxide nanoparticles induce trained immunity to protect mice against sepsis

Y Pan, J Li, X Xia, J Wang, Q Jiang, J Yang, H Dou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Innate immune memory, also termed “trained immunity”, is thought to protect
against experimental models of infection, including sepsis. Trained immunity via …

Six potential biomarkers in septic shock: a deep bioinformatics and prospective observational study

C Kong, Y Zhu, X Xie, J Wu, M Qian - Frontiers in Immunology, 2023 - frontiersin.org
Background Septic shock occurs when sepsis is related to severe hypotension and leads to
a remarkable high number of deaths. The early diagnosis of septic shock is essential to …

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement …

H Wang, X Kang, Y Shi, Z Bai, J Lv, J Sun, H Pei - Renal Failure, 2020 - Taylor & Francis
Background Acute kidney injury (AKI) is the most common cause of organ failure in multiple
organ dysfunction syndrome (MODS) and is associated with increased mortality. This study …

Dexmedetomidine-mediated protection against septic liver injury depends on TLR4/MyD88/NF-κB signaling downregulation partly via cholinergic anti-inflammatory …

S Zi, JH Li, L Liu, C Deng, X Ao, D Chen… - International …, 2019 - Elsevier
Background Uncontrolled inflammatory responses exacerbate the pathogenesis of septic
acute liver injury (ALI), posing a lethal threat to the host. Dexmedetomidine (DEX) has been …