[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

[HTML][HTML] Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F Xie, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

[HTML][HTML] Molecular mechanisms and signaling pathways involved in sertoli cell proliferation

SB Meroni, MN Galardo, G Rindone, A Gorga… - Frontiers in …, 2019 - frontiersin.org
Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in
regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited …

[HTML][HTML] Androgen receptor structure, function and biology: from bench to bedside

RA Davey, M Grossmann - The clinical biochemist reviews, 2016 - ncbi.nlm.nih.gov
The actions of androgens such as testosterone and dihydrotestosterone are mediated via
the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of …

Steroids in teleost fishes: A functional point of view

J Tokarz, G Möller, MH de Angelis, J Adamski - Steroids, 2015 - Elsevier
Steroid hormones are involved in the regulation of a variety of processes like embryonic
development, sex differentiation, metabolism, immune responses, circadian rhythms, stress …

Role of zinc in female reproduction

TB Garner, JM Hester, A Carothers… - Biology of …, 2021 - academic.oup.com
Zinc is a critical component in a number of conserved processes that regulate female germ
cell growth, fertility, and pregnancy. During follicle development, a sufficient intracellular …

Maternal investment in fish oocytes and eggs: the molecular cargo and its contributions to fertility and early development

E Lubzens, J Bobe, G Young, CV Sullivan - Aquaculture, 2017 - Elsevier
The production of fertile eggs with the capacity to develop into larvae and subsequently into
marketable fish is centrally important to the aquaculture industry. This entails not only the …

Identification and characterization of membrane androgen receptors in the ZIP9 zinc transporter subfamily: II. Role of human ZIP9 in testosterone-induced prostate and …

P Thomas, Y Pang, J Dong, AH Berg - Endocrinology, 2014 - academic.oup.com
Recently, we discovered a cDNA in teleost ovarian follicle cells belonging to the zinc
transporter ZIP9 subfamily (SLC39A9) encoding a protein with characteristics of a …

Toward unzipping the ZIP metal transporters: structure, evolution, and implications on drug discovery against cancer

J Hu - The FEBS journal, 2021 - Wiley Online Library
The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …

[HTML][HTML] The molecular mechanism of sex hormones on Sertoli cell development and proliferation

W Shah, R Khan, B Shah, A Khan, S Dil… - Frontiers in …, 2021 - frontiersin.org
Sustaining and maintaining the intricate process of spermatogenesis is liable upon
hormones and growth factors acting through endocrine and paracrine pathways. The Sertoli …