Early diagnosis of neurodegenerative diseases: what has been undertaken to promote the transition from PET to fluorescence tracers

N Bisi, L Pinzi, G Rastelli, N Tonali - Molecules, 2024 - mdpi.com
Alzheimer's Disease (AD) and Parkinson's Disease (PD) represent two among the most
frequent neurodegenerative diseases worldwide. A common hallmark of these pathologies …

Gasotransmitter nitric oxide imaging in Alzheimer's disease and glioblastoma with diamino-cyclic-metalloiridium phosphorescence probes

H Ding, L Luo, L Su, J Chen, Y Li, L Hu, K Luo… - Biosensors and …, 2024 - Elsevier
Nitric Oxide (NO), a significant gasotransmitter in biological systems, plays a crucial role in
neurological diseases and cancer. Currently, there is a lack of effective methods for rapidly …

[HTML][HTML] Visulization of peroxynitrite variation for accurate diagnosis and assessing treatment response of hepatic fibrosis using a Golgi-targetable ratiometric …

T Zhang, Z Li, M Qin, J Zhang, Y Sun, C Liu - Journal of Photochemistry and …, 2024 - Elsevier
Hepatic fibrosis (HF) is caused by persistent inflammation, which is closely associated with
hepatic oxidative stress. Peroxynitrite (ONOO−) is significantly elevated in HF, which would …

Intraoperative tumor mapping using pyridine-carbazole based multifunctional fluorescent probes for precise resection and photodynamic therapeutics

L Su, X Zhu, H Ding, L Hu, J Chen, S Qi, K Luo… - Sensors and Actuators B …, 2024 - Elsevier
Precise intraoperative tumor localization plays a pivotal role in the quest for refined cancer
therapeutics. Addressing this, we have developed a series of novel pyridine-carbazole …

Novel pyrrolidine-alkylamino-substituted dicyanoisophorone derivatives as near-infrared fluorescence probe for imaging β-amyloid in vitro and in vivo

H Zhou, J Zhai, H Gong, R Fang, Y Zhao, W Luo - Analytica Chimica Acta, 2024 - Elsevier
Background The formation of amyloid-β (Aβ) plaques is one of the key neuropathological
hallmarks of Alzheimer's disease (AD). Near-infrared (NIR) probes show great potential for …

A near-infrared fluorescent probe with two-photon excitation for in situ imaging of NQO1 in human colorectum cancer tissue

W Jiang, W An, Z Huang, C Xu, Q Shen, C Pu, S Zhang… - Talanta, 2024 - Elsevier
Colorectum cancer has become one of the most fatal cancer diseases, in which NAD (P) H:
quinone oxidoreductase 1 (NQO1) plays a role in intracellular free radical reduction and …

High pH stability and detection of α-synuclein using an EGFET biosensor with an HfO2 gate deposited by high-power pulsed magnetron sputtering

CM Yang, CH Wei, F Ughi, JY Chang… - Sensors and Actuators B …, 2024 - Elsevier
In this research, hafnium oxide (HfO 2) was first fabricated in an in-house-developed high-
power pulsed magnetron sputtering system (HiPIMS) functionalized for application as a high …