Ethanol precipitation is a purification process widely used in the purification of Chinese
medicine concentrates. This article reviews the research progress on the process …

This paper was designed to assess the value of quality by design (QbD) to improve the
manufacturing process understanding of botanical drug products. Ethanol precipitation, a …

The solubilities of (2 R, 3 S, 4 R)-2, 3, 4, 5-tetrahydroxypentanal (xylose),(2 R, 3 R, 4 R, 5 R)-
2, 3, 5, 6-tetrahydroxy-4-[(2 R, 3 R, 4 S, 5 S, 6 R)-3, 4, 5-trihydroxy-6-(hydroxymethyl) oxan-2 …

Traditional Chinese medicine (TCM) products are usually manufactured through batch
processes. To improve batch-to-batch reproducibility, the feasible approaches for real-time …

A solvent recycling reflux extraction process for Panax notoginseng was optimized using a
design space approach to improve the batch-to-batch consistency of the extract. Saponin …

Ethanol precipitation is a widely applied separation technology in the production of botanical
medicines, but the research on this technology is few. In this work, ethanol precipitation is …

The alkaline ethanol precipitation process is investigated as an example of a technique for
the removal of tannins extracted from Salviae miltiorrhizae Radix et Rhizoma for the …

Introduction The concept of quality by design (QbD) has been widely accepted and applied
in the pharmaceutical manufacturing industry. There are still two key issues to be addressed …

Gardeniae Fructus is widely used in the pharmaceutical industry, and many studies have
confirmed its medical and economic value. In this study, samples collected from different …

3, 4-Dihydroxybenzaldehyde (protocatechuic aldehyde),(E)-3-(3, 4-dihydroxyphenyl) prop-2-
enoic acid (caffeic acid),(2 S, 3 R, 4 S, 5 R, 6 R)-6-(hydroxymethyl) oxane-2, 3, 4, 5-tetrol (d …