Bariatric surgery, which is an effective treatment for obesity, and gastrectomy, which is the
primary treatment method for gastric cancer, alter the anatomy and physiology of the …

Dabigatran, a direct thrombin inhibitor, has robust data for the treatment of deep venous
thrombosis and pulmonary embolism, stroke prevention in non-valvular atrial fibrillation, and …

Introduction Dabigatran is a direct oral anticoagulant (DOAC) used for the treatment of
several thrombotic conditions. To date, very few pharmacogenetic studies on dabigatran …

Introduction In recent years, the traditional treatments for thrombotic diseases, heparin and
warfarin, are increasingly being replaced by novel oral anticoagulants offering convenient …

Thrombin inhibition therapy is a practical strategy to reduce thrombotic and cardiovascular
risks via blocking the formation of blood clots. This study aimed to identify naturally occurring …

Aims Blood coagulation is one of the most important host-defending mechanisms in vivo by
maintaining the blood pressure after injury. However, besides maintaining homeostasis …

Background SAR107375E is a direct dual inhibitor of both Factor Xa and Factor IIa and has
shown potent anticoagulation activity in vitro and animals. This study evaluated the safety …

Heart Team emerged as an important tool in the cardiovascular care, improving the
efficiency of decision-making process. In addition to the benefits in patient care, it …

Abstract Background and Objective Dabigatran etexilate is a non-vitamin K antagonist oral
anticoagulant (NOAC) that is used to prevent stroke and systemic embolism in adults with …

Direct oral anticoagulants (DOACs) have revolutionized the field of anticoagulation in the
last decade, mainly due to their fixed dosing, rapid onset of anticoagulant effect, and non …