Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

The immunotherapy of cancer has made significant strides in the past few years due to
improved understanding of the underlying principles of tumor biology and immunology …

Background The combination of galunisertib, a transforming growth factor (TGF)-β receptor
(R) 1 kinase inhibitor, and lomustine was found to have antitumor activity in murine models …

The outcome prediction in cancer is usually achieved by evaluating tissue samples obtained
during surgical removal of the primary tumor focusing on their histopathological …

Recently, a firmer understanding of tumor immunology and tumor escape mechanisms has
led to the development of immune checkpoint inhibitors, antibodies against programmed …

Cardiovascular diseases are the leading cause of premature death and disability worldwide,
with both genetic and environmental determinants. While genome-wide association studies …

A continual trend of annual growth can be seen within research devoted to the discovery
and validation of disease biomarkers within both the natural and clinical sciences. This …

Polychlorinated biphenyls (PCBs) are one of the original twelve classes of toxic chemicals
covered by the Stockholm Convention on Persistent Organic Pollutants (POP), an …

Cancer vaccines have undergone a renaissance because of recent clinical trials showing
promising immunologic data and some clinical benefit to patients. Current trials exploiting …

Recently the prevalence of obesity has increased dramatically across much of the world.
Obesity, as a complex, multifactorial disease, and its health consequences probably result …