Exploring the potential role of circulating microRNAs as biomarkers for predicting clinical response to neoadjuvant therapy in breast cancer

LM Ruiz-Manriquez, C Villarreal-Garza… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC) is a leading cause of cancer-related deaths among women worldwide.
Neoadjuvant therapy (NAT) is increasingly being used to reduce tumor burden prior to …

Cancer stem cells: advances in knowledge and implications for cancer therapy

X Chu, W Tian, J Ning, G Xiao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

METTL3/LINC00662/miR-186-5p feedback loop regulates docetaxel resistance in triple negative breast cancer

L Jing, L Lan, Z Mingxin, Z Zhaofeng - Scientific Reports, 2022 - nature.com
Insight into the mechanism of docetaxel resistance in breast cancer may help to improve
prognosis. We aimed to investigate the role of N6-methyladenosine (m6A) and the …

PITX1 suppresses osteosarcoma metastasis through exosomal LINC00662-mediated M2 macrophage polarization

Y Zhang, Y Chen, C Chen, H Guo, C Zhou… - Clinical & experimental …, 2023 - Springer
Paired-like homeodomain transcription factor 1 (PITX1) is frequently downregulated in
cancers, including osteosarcoma (OS). However, its role in OS remains unknown. Therefore …

LINC00662 Promotes Aggressive Traits by Modulating OCT4 Expression through miR-335-5p in Gallbladder Cancer Cells

P Pérez-Moreno, I Riquelme, C Bizama… - International Journal of …, 2024 - mdpi.com
Long non-coding RNAs (lncRNAs) are nucleotide sequences that participate in different
biological processes and are associated with different pathologies, including cancer. Long …

The Multifaceted Role of SOX2 in Breast and Lung Cancer Dynamics

K Hushmandi, SH Saadat, S Mirilavasani… - … -Research and Practice, 2024 - Elsevier
Breast and lung cancers are leading causes of death among patients, with their global
mortality and morbidity rates increasing. Conventional treatments often prove inadequate …

Linc00662 sponges miR-15b-5p to promote hypopharyngeal squamous cell carcinoma progression by facilitating cancer stem cell-like phenotypes

B Zhang, Q Ye - Journal of Cancer, 2024 - jcancer.org
Background: Long non-coding RNAs (lncRNAs) are associated with multiple head and neck
tumors and play important roles in cancer. This study explored the molecular mechanism of …

Silencing the lncRNA EBLN3P alleviates poor prognosis in patients with invasive breast cancer by directly targeting miR-144-3p

M Hu, M Zhang, X Qi, L Yuan, Z Wu, Y Tian… - Journal of Environmental … - dl.begellhouse.com
Background: The incidence of breast cancer, a malignant tumor that causes more harm to
women, is increasing year by year, affecting women at a younger age. This paper describes …