Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review

CC Maresch, DC Stute, MG Alves… - Human …, 2018 - academic.oup.com
BACKGROUND Hyperglycemia can result from a loss of pancreatic beta-cells or a decline in
their function leading to decreased insulin secretion or may arise from insulin resistance and …

The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

K San Tang - Life sciences, 2019 - Elsevier
Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious
attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related …

[HTML][HTML] The effects of separate and combined treatment of male rats with type 2 diabetes with metformin and orthosteric and allosteric agonists of luteinizing hormone …

AA Bakhtyukov, KV Derkach, VN Sorokoumov… - International Journal of …, 2021 - mdpi.com
In men with type 2 diabetes mellitus (T2DM), steroidogenesis and spermatogenesis are
impaired. Metformin and the agonists of luteinizing hormone/human chorionic gonadotropin …

Abnormalities in sex hormones and sexual dysfunction in males with diabetes mellitus: A mechanistic insight

N Andlib, M Sajad, R Kumar, SC Thakur - Acta Histochemica, 2023 - Elsevier
Diabetes is a considerate metabolic disorder that can lead to a series of complications,
involving the malfunctioning of the reproductive system of males. It has been observed that …

[HTML][HTML] Nanotechnology in the treatment of diabetic complications: a comprehensive narrative review

Y He, A Al-Mureish, N Wu - Journal of Diabetes Research, 2021 - hindawi.com
In today's society, the prevention and treatment of diabetes mellitus and its subsequent
complications have brought trouble to human beings. Complications caused by diabetes …

Molecular mechanisms and signaling pathways involved in the nutritional support of spermatogenesis by Sertoli cells

L Crisóstomo, MG Alves, A Gorga, M Sousa… - Sertoli Cells: Methods …, 2018 - Springer
Sertoli cells play a central role in spermatogenesis. They maintain the blood-testis barrier,
an essential feature of seminiferous tubules which creates the proper environment for the …

The effect of metformin treatment on the basal and gonadotropin‐stimulated steroidogenesis in male rats with type 2 diabetes mellitus

KV Derkach, AA Bakhtyukov, IV Romanova… - Andrologia, 2020 - Wiley Online Library
Type 2 diabetes mellitus impairs reproductive functions in men, and important tasks are
deciphering the mechanisms of testicular dysfunctions in diabetes and the search of …

Diet during early life defines testicular lipid content and sperm quality in adulthood

L Crisóstomo, RA Videira, I Jarak… - American Journal …, 2020 - journals.physiology.org
Childhood obesity is a serious concern associated with ill health later in life. Emerging data
suggest that obesity has long-term adverse effects upon male sexual and reproductive …

Chlorpyrifos-induced reproductive toxicity in rats could be partly relieved under high-fat diet

J Li, G Pang, F Ren, B Fang - Chemosphere, 2019 - Elsevier
The widely used pesticide, chlorpyrifos, was found to inhibit the secretion of sex hormones
and decrease the count and quality of sperm. A high-fat diet damaged the reproductive …

Chlorpyrifos induces metabolic disruption by altering levels of reproductive hormones

J Li, F Ren, Y Li, J Luo, G Pang - Journal of agricultural and food …, 2019 - ACS Publications
Chlorpyrifos (CPF) is a widely used organophosphorus pesticide and detected frequently in
fruits, vegetables, as well as in urine and blood in humans. Studies have suggested that …