Vasoplegia treatments: the past, the present, and the future

B Levy, C Fritz, E Tahon, A Jacquot, T Auchet… - Critical care, 2018 - Springer
Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic,
cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving …

Vascular hyporesponsiveness to vasopressors in septic shock: from bench to bedside

B Levy, S Collin, N Sennoun, N Ducrocq… - Intensive care …, 2010 - Springer
Purpose To delineate some of the characteristics of septic vascular hypotension, to assess
the most commonly cited and reported underlying mechanisms of vascular …

Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial

F Lauzier, B Lévy, P Lamarre, O Lesur - Intensive care medicine, 2006 - Springer
Objective To compare the effects of arginine-vasopressin (AVP) and norepinephrine (NE) on
hemodynamic variables, organ dysfunction, and adverse events in early hyperdynamic …

Vasopressin: mechanisms of action on the vasculature in health and in septic shock

LK Barrett, M Singer, LH Clapp - Critical care medicine, 2007 - journals.lww.com
Background: Vasopressin is essential for cardiovascular homeostasis, acting via the kidney
to regulate water resorption, on the vasculature to regulate smooth muscle tone, and as a …

Multimodal strategy to counteract vasodilation in septic shock

M Leone, S Einav, E Antonucci, F Depret… - … Critical Care & Pain …, 2023 - Elsevier
Early initiation of a multimodal treatment strategy in the management of vasopressors during
septic shock has been advocated to reduce delays in restoring adequate organ perfusion …

Bench-to-bedside review: vasopressin in the management of septic shock

JA Russell - Critical Care, 2011 - Springer
This review of vasopressin in septic shock differs from previous reviews by providing more
information on the physiology and pathophysiology of vasopressin and vasopressin …

Vasopressin and terlipressin in adult vasodilatory shock: a systematic review and meta-analysis of nine randomized controlled trials

A Serpa Neto, AP Nassar, SO Cardoso, JA Manetta… - Critical care, 2012 - Springer
Introduction Catecholamines are the most used vasopressors in vasodilatory shock.
However, the development of adrenergic hyposensitivity and the subsequent loss of …

Advances in the management of sepsis and the understanding of key immunologic defects

LP Skrupky, PW Kerby, RS Hotchkiss - The Journal of the American …, 2011 - pubs.asahq.org
Anesthesiologists are increasingly confronting the difficult problem of caring for patients with
sepsis in the operating room and in the intensive care unit. Sepsis occurs in more than …

Vasopressin in pediatric vasodilatory shock: a multicenter randomized controlled trial

K Choong, D Bohn, DD Fraser, I Gaboury… - American journal of …, 2009 - atsjournals.org
Rationale: Vasopressin has been proposed as a potent vasoactive agent in the treatment of
vasodilatory shock in adults and children. The objective of this trial was to evaluate the …

[HTML][HTML] Comparison of norepinephrine and terlipressin vs norepinephrine alone for management of septic shock: a randomized control study

P Sahoo, N Kothari, S Goyal, A Sharma… - Indian Journal of …, 2022 - ncbi.nlm.nih.gov
Materials and methods In this prospective, randomized control trial, 50 adult patients with
septic shock were randomized into two groups. Group I received a combination of injection …