PCR in Forensic Science: A Critical Review
The polymerase chain reaction (PCR) has played a fundamental role in our understanding
of the world, and has applications across a broad range of disciplines. The introduction of …
of the world, and has applications across a broad range of disciplines. The introduction of …
Analyzing degraded DNA and challenging samples using the ForenSeq™ DNA Signature Prep kit
V Sharma, DA van der Plaat, Y Liu, E Wurmbach - Science & Justice, 2020 - Elsevier
Typing short tandem repeats (STRs) is the basis for human identification in current forensic
testing. The standard method uses capillary electrophoresis (CE) to separate amplicons by …
testing. The standard method uses capillary electrophoresis (CE) to separate amplicons by …
Evidentiary evaluation of single cells renders highly informative forensic comparisons across multifarious admixtures
The consistency between DNA evidence and person (s) of interest (PoI) is summarized by a
likelihood ratio (LR): the probability of the data given the PoI contributed divided by the …
likelihood ratio (LR): the probability of the data given the PoI contributed divided by the …
Evaluation of four commercial quantitative real-time PCR kits with inhibited and degraded samples
DNA quantification is a vital step in forensic DNA analysis to determine the optimal input
amount for DNA typing. A quantitative real-time polymerase chain reaction (qPCR) assay …
amount for DNA typing. A quantitative real-time polymerase chain reaction (qPCR) assay …
Successful nuclear DNA profiling of rootless hair shafts: a novel approach
KS Grisedale, GM Murphy, H Brown, MR Wilson… - International journal of …, 2018 - Springer
Historically, rootless hair shaft samples submitted to a forensic laboratory for DNA analysis
are reserved for mitochondrial DNA (mtDNA) analysis due to the presence of highly …
are reserved for mitochondrial DNA (mtDNA) analysis due to the presence of highly …
Improved reverse transcription-recombinase polymerase amplification assay for blood mRNA screening: comparison with one-step RT-qPCR assay
S Kubo, H Niimi, I Kitajima - Forensic Science International: Genetics, 2023 - Elsevier
Abstract mRNA profiling is effective for body fluid identification because of its sensitivity,
specificity, and multiplexing capability. Body fluid mRNA markers can typically be detected …
specificity, and multiplexing capability. Body fluid mRNA markers can typically be detected …
[HTML][HTML] Isolation and genetic analysis of pure cells from forensic biological mixtures: The precision of a digital approach
F Fontana, C Rapone, G Bregola, R Aversa… - Forensic Science …, 2017 - Elsevier
Latest genotyping technologies allow to achieve a reliable genetic profile for the offender
identification even from extremely minute biological evidence. The ultimate challenge occurs …
identification even from extremely minute biological evidence. The ultimate challenge occurs …
Assessing DNA Degradation through Differential Amplification Efficiency of Total Human and Human Male DNA in a Forensic qPCR Assay
E Chierto, S Aneli, N Nocco, A Riem, M Onofri… - Genes, 2024 - mdpi.com
The assessment of degradation is crucial for the analysis of human DNA samples isolated
from forensic specimens. Forensic quantitative PCR (qPCR) assays can include multiple …
from forensic specimens. Forensic quantitative PCR (qPCR) assays can include multiple …
Evaluation of ForenSeq™ Signature Prep Kit B on predicting eye and hair coloration as well as biogeographical ancestry by using Universal Analysis Software (UAS) …
This study examined 266 individuals from various populations including African American,
East Asian, South Asian, European, and mixed populations to evaluate the ForenSeq™ …
East Asian, South Asian, European, and mixed populations to evaluate the ForenSeq™ …