An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

Interventions to improve the appropriate use of polypharmacy for older people

A Rankin, CA Cadogan, SM Patterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

[HTML][HTML] Retracted: effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis

BR da Costa, S Reichenbach, N Keller, L Nartey… - The Lancet, 2016 - thelancet.com
Background Non-steroidal anti-inflammatory drugs (NSAIDs) are the backbone of
osteoarthritis pain management. We aimed to assess the effectiveness of different …

Interventions to improve the appropriate use of polypharmacy in older people: a Cochrane systematic review

JA Cooper, CA Cadogan, SM Patterson, N Kerse… - BMJ open, 2015 - bmjopen.bmj.com
Objective To summarise the findings of an updated Cochrane review of interventions aimed
at improving the appropriate use of polypharmacy in older people. Design Cochrane …

Potentially inappropriate prescribing and its associations with health‐related and system‐related outcomes in hospitalised older adults: a systematic review and meta …

AB Mekonnen, B Redley, B de Courten… - British journal of …, 2021 - Wiley Online Library
Aims To synthesise associations of potentially inappropriate prescribing (PIP) with health‐
related and system‐related outcomes in inpatient hospital settings. Methods Six electronic …

Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review

E Tommelein, E Mehuys, M Petrovic, A Somers… - European journal of …, 2015 - Springer
Background Potentially inappropriate prescribing (PIP) is one of the main risk factors for
adverse drug events (ADEs) in older people. Purpose This systematic literature review aims …

[HTML][HTML] Appropriate polypharmacy and medicine safety: when many is not too many

CA Cadogan, C Ryan, CM Hughes - Drug safety, 2016 - Springer
The use of multiple medicines (polypharmacy) is increasingly common in middle-aged and
older populations. Ensuring the correct balance between the prescribing of 'many'drugs and …

Application of the STOPP/START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical …

B Hill‐Taylor, I Sketris, J Hayden… - Journal of clinical …, 2013 - Wiley Online Library
What is known and Objective Potentially inappropriate prescribing (PIP) has significant
clinical, humanistic and economic impacts. Identifying PIP in older adults may reduce their …

Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria

PF Gallagher, MN O'connor… - Clinical Pharmacology & …, 2011 - Wiley Online Library
Inappropriate prescribing is particularly common in older patients and is associated with
adverse drug events (ADEs), hospitalization, and wasteful utilization of resources. We …

Polypharmacy, adverse drug reactions, and geriatric syndromes

BM Shah, ER Hajjar - Clinics in geriatric medicine, 2012 - geriatric.theclinics.com
The older population, composed of adults aged 65 years or older, is the fastest growing
segment of the United States population. The Administration of Aging of the United States …