Orthodontic pain is an inflammatory pain that is initiated by orthodontic force-induced
vascular occlusion followed by a cascade of inflammatory responses, including vascular …

Pain caused by acute pulpitis (AP) is a common symptom in clinical settings. However, its
underlying mechanisms have largely remained unknown. Using AP model, we …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to relieve pain during
orthodontic treatments; however, the possible inhibition of orthodontic tooth movement …

Simvastatin (SMV) could increase tooth anchorage during orthodontic tooth movement
(OTM). However, previous studies on its bone‐specific anabolic and anti‐inflammation …

We previously demonstrated that accurate regulation of isometric contraction (IC) of jaw-
closing muscles to counteract the ramp load applied to the jaw in the jaw-opening direction …

Psychological stress is a risk factor for the development of musculoskeletal pain of the head
and neck; however, the basis for this relationship remains uncertain. This study tested the …

Objective. To explore the mechanism of catechol-O-methyltransferase (COMT) in tooth
movement pain. Methods. The experimental groups were randomly allocated into the …

The aim of the study was to investigate the effect of emotional stress on apical root
resorption (ARR) and tooth displacement during orthodontic tooth movement in rats. A …

Objective: To test the efficacy of an animal model of pain and stress and evaluate the effects
of celecoxib administered when orthodontic force is applied. Materials and Methods: A 20-g …

Objective: To test the hypothesis that peripheral N-methyl-D-aspartate (NMDA) receptors
play a role in pain induced by experimental tooth movement. Materials and Methods: Male …