Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

Cutaneous melanin pigment plays a critical role in camouflage, mimicry, social
communication, and protection against harmful effects of solar radiation. Melanogenesis is …

The classification of histamine receptors has to date been based on rigorous classical
pharmacological analysis, and as yet, the classification of the three histamine receptors that …

The diverse physiological functions of histamine are mediated through distinct histamine
receptors. Mast cells are major producers of histamine, yet effects of histamine on mast cells …

Verkhratsky, Alexej, Richard K. Orkand, and Helmut Kettenmann. Glial Calcium:
Homeostasis and Signaling Function. Physiol. Rev. 78: 99–141, 1998.—Glial cells respond …

The important roles of histamine in body physiology and various pathologic events have
been well established, whereas new and exciting findings are still being uncovered …

Many pathological processes, including those causing allergies and autoimmune diseases,
are associated with the presence of specialized subsets of T helper cells (TH1 and TH2) at …

Recently cDNA encoding the histamine H3 receptor was isolated after 15 years of
considerable research. However, several studies have proposed heterogeneity of the H3 …

Histamine mediates its physiological function through binding to four known histamine
receptors. Here, we describe the first selective antagonist of the histamine H4 receptor, the …

Histamine is a potent bioamine with multiple activities in various pathological and
physiological conditions. In addition to its well-characterised effects in the acute …