Developmental changes in NMDA receptor subunit composition at ON and OFF bipolar cell synapses onto direction-selective retinal ganglion cells

BK Stafford, SJH Park, KY Wong… - Journal of …, 2014 - Soc Neuroscience
In the developing mouse retina, spontaneous and light-driven activity shapes bipolar→
ganglion cell glutamatergic synapse formation, beginning around the time of eye-opening …

Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements

SR Tummala, A Neinstein, ME Fina… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: L-type voltage gated calcium channels in retina localize primarily at the
presynaptic active zones of photoreceptors and bipolar cells where they modulate glutamate …

Chemogenetic suppression of GnRH neurons during pubertal development can alter adult GnRH neuron firing rate and reproductive parameters in female mice

EA Dulka, RA DeFazio, SM Moenter - Eneuro, 2020 - eneuro.org
Gonadotropin-releasing hormone (GnRH) neurons control anterior pituitary, and thereby
gonadal, function. GnRH neurons are active before outward indicators of puberty appear …

Crx is posttranscriptionally regulated by light stimulation in postnatal rat retina

Y Wu, J Qiu, S Chen, X Chen, J Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Cone rod homeobox (Crx) plays a key role at the center of a regulatory network that
coordinates many pathways in the retina. Its abnormal expression induces retinal disorders …

Модифицирующее лечение дегенеративных заболеваний сетчатки. Часть 1. Адаптивная и неадаптивная пластичность сетчатки

МВ Зуева, НВ Нероева, ЛА Катаргина… - Российский …, 2023 - roj.igb.ru
Аннотация Структурная пластичность сетчатки проявляется при ее повреждении
различной природы, ответ на которое во многих случаях идентичен на клеточном и …

Essential functions of MLL1 and MLL2 in retinal development and cone cell maintenance

C Sun, X Zhang, PA Ruzycki, S Chen - Frontiers in Cell and …, 2022 - frontiersin.org
MLL1 (KMT2A) and MLL2 (KMT2B) are homologous members of the mixed-lineage
leukemia (MLL) family of histone methyltransferases involved in epigenomic transcriptional …

[HTML][HTML] Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation

SY Chaney, S Mukherjee, A Giddabasappa… - Molecular …, 2016 - ncbi.nlm.nih.gov
Purpose Studies of neuronal development in the retina often examine the stages of
proliferation, differentiation, and synaptic development, albeit independently. Our goal was …

Distribution and Functional Characteristics of Voltage-Gated Sodium Channels in Immature Cochlear Hair Cells

Y Zhou, C Xia, M Yin, X Wang, H Wu, Y Ji - Neuroscience Bulletin, 2020 - Springer
Voltage-gated sodium channels (VGSCs) are transiently expressed in cochlear hair cells
before hearing onset and play an indispensable role in shaping spontaneous activity. In this …

Neuronal Cultures: Exploring Biophysics, Complex Systems, and Medicine in a Dish

J Soriano i Fradera - Biophysica, 2023, vol. 3, num. 1, p. 181-202, 2023 - diposit.ub.edu
Neuronal cultures are one of the most important experimental models in modern
interdisciplinary neuroscience, allowing to investigate in a control environment the …

A Bayesian framework for comparing the structure of spontaneous correlated activity recorded under different conditions

CS Cutts, SJ Eglen - bioRxiv, 2016 - biorxiv.org
Distant-dependent correlations in spontaneous retinal activity are thought to be instructive in
the development of the retinotopic map and eye-specific segregation maps. Many studies …