Therapeutic anticoagulation is indicated for a variety of circumstances and conditions in
several fields of medicine to prevent or treat venous and arterial thromboembolism …

Hemodialysis, the most common modality of renal replacement therapy, is critically required
to remove uremic toxins from the blood of patients with end-stage kidney disease. However …

Heparins are widely used anticoagulants for surgical procedures and extracorporeal
therapies. However, all of them have bleeding risks. Protamine sulfate, the only clinically …

Dialysis membranes capable of preventing coagulation and inflammation and achieving
high toxin clearances are highly desired for clinical hemodialysis. Here, we constructed an …

An adequate knowledge of anticoagulants used to prevent clotting in the extracorporeal
circuit is crucial to provide optimal hemodialysis. Drugs can potentially prevent …

A high protein retention polyethersulfone (PES) membrane was prepared by nonsolvent-
induced phase separation and surface coating, which exhibited enhanced …

Hemodialysis is a life-sustaining therapy for millions of people worldwide. However, despite
considerable technical and scientific improvements, results are still not fully satisfactory in …

Unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs) are widely
applied for surgical procedures and extracorporeal therapies, which, however, suffer …

Maintaining patency of the extracorporeal hemodialysis (HD) circuit is a prerequisite to
perform HD. Unfractionated heparin and low-molecular-weight heparins are the most used …

Current hemodialysis requires a dilemmatic balance between under-and over-
heparinization to prevent extracorporeal circuit clotting and bleeding complications. Here we …