Flavonoids as promising neuroprotectants and their therapeutic potential against Alzheimer's disease
T Minocha, H Birla, AA Obaid, V Rai… - Oxidative Medicine …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is one of the serious and progressive neurodegenerative
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …
disorders in the elderly worldwide. Various genetic, environmental, and lifestyle factors are …
Redox imbalance as a common pathogenic factor linking hearing loss and cognitive decline
F Paciello, C Ripoli, AR Fetoni, C Grassi - Antioxidants, 2023 - mdpi.com
Experimental and clinical data suggest a tight link between hearing and cognitive functions
under both physiological and pathological conditions. Indeed, hearing perception requires …
under both physiological and pathological conditions. Indeed, hearing perception requires …
Curcumin interacts with α-synuclein condensates to inhibit amyloid aggregation under phase separation
B Xu, J Chen, Y Liu - ACS omega, 2022 - ACS Publications
The amyloid aggregation of α-synuclein (α-Syn) is highly associated with Parkinson's
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …
disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies …
Myricetin inhibits α‐synuclein amyloid aggregation by delaying the liquid‐to‐solid phase transition
B Xu, X Mo, J Chen, H Yu, Y Liu - Chembiochem, 2022 - Wiley Online Library
The aggregation of α‐synuclein (α‐Syn) is a critical pathological hallmark of Parkinson's
disease (PD). Prevention of α‐Syn aggregation has become a key strategy for treating PD …
disease (PD). Prevention of α‐Syn aggregation has become a key strategy for treating PD …
A new framework for drug–disease association prediction combing light-gated message passing neural network and gated fusion mechanism
BM Liu, YL Gao, DJ Zhang, F Zhou… - Briefings in …, 2022 - academic.oup.com
With the development of research on the complex aetiology of many diseases,
computational drug repositioning methodology has proven to be a shortcut to costly and …
computational drug repositioning methodology has proven to be a shortcut to costly and …
Neuro-Nutraceutical Polyphenols: How Far Are We?
MT Gentile, I Camerino, L Ciarmiello, P Woodrow… - Antioxidants, 2023 - mdpi.com
The brain, composed of billions of neurons, is a complex network of interacting dynamical
systems controlling all body functions. Neurons are the building blocks of the nervous …
systems controlling all body functions. Neurons are the building blocks of the nervous …
Investigating role of plumbagin in preventing neurodegenerative diseases via inhibiting microtubule affinity regulating kinase 4
Microtubule affinity regulating kinase 4 (MARK4) is associated with the progression of
neurodegeneration, cancer, cardiovascular diseases, obesity and other life-threatening …
neurodegeneration, cancer, cardiovascular diseases, obesity and other life-threatening …
Recent progress in research on mechanisms of action of natural products against Alzheimer's disease: Dietary plant polyphenols
Y Wang, K Wang, J Yan, Q Zhou, X Wang - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is an incurable degenerative disease of the central nervous
system and the most common type of dementia in the elderly. Despite years of extensive …
system and the most common type of dementia in the elderly. Despite years of extensive …
Is Caperatic Acid the Only Compound Responsible for Activity of Lichen Platismatia glauca within the Nervous System?
E Studzińska-Sroka, A Majchrzak-Celińska… - Antioxidants, 2022 - mdpi.com
Lichens are a source of various biologically active compounds. However, the knowledge
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …
about them is still scarce, and their use in medicine is limited. This study aimed to investigate …
Nanotechnology in the diagnostic and therapy for Alzheimer's disease
A Panghal, SJS Flora - Biochimica et Biophysica Acta (BBA)-General …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by β-
amyloid plaque, intraneuronal tangles, significant neuronal loss and cognitive deficit …
amyloid plaque, intraneuronal tangles, significant neuronal loss and cognitive deficit …