Reversal of Pharmacologically Induced Mydriasis with Phentolamine Ophthalmic Solution

JS Pepose, D Wirta, D Evans, B Withers, K Rahmani… - Ophthalmology, 2024 - Elsevier
PURPOSE Evaluate safety and efficacy of 0.75% phentolamine ophthalmic solution (POS),
an alpha-1 antagonist, in reversal of pharmacologically induced mydriasis. DESIGN Two …

Subgroup Analysis from a Phase 1/2 Randomized Clinical Trial of 2.6% EDTA Ophthalmic Solution in Patients with Age-Related Cataract

T Kuboi, RS Chuck, R PINEDA II, R Bhushan… - American Journal of …, 2024 - Elsevier
Purpose To explore the efficacy of topical 2.6% EDTA ophthalmic solution (C-KAD) as a
treatment to improve visual function for the subgroup of patients with loss of contrast …

Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance

A Meyer - US Patent 11,717,510, 2023 - Google Patents
The invention provides methods, compositions, and kits containing phentolamine for
improving visual performance. In particular, the invention provides improvement in visual …

Highly pure phentolamine mesylate and methods for making same

DC Oniciu - US Patent 11,566,005, 2023 - Google Patents
C07D233/04—Heterocyclic compounds containing 1, 3-diazole or hydrogenated 1, 3-
diazole rings, not condensed with other rings having one double bond between ring …

Aberrazioni e visione notturna: correlazioni e implicazioni

S CANDIBA - thesis.unipd.it
Questo studio si propone di analizzare e confrontare le aberrazioni oculari (prendendo in
considerazione l'indice globale RMS) con i disturbi della visione notturna, indagati …

[HTML][HTML] Eye Dilation Dilemma: Strategies for Drop-Defying Patients

AG Kabat - eyesoneyecare.com
Picture the following: It'sa routine Tuesday morning at work. Your first scheduled
appointment is a new patient. He's a 33-year-old carpenter, in for a routine eye examination …

[HTML][HTML] Shrinking Night Vision Disturbances

J SCHWEITZER - presbyopiaphysician.com
NIGHT VISION DISTURBANCES (NVDs) constitute a challenging array of quality-of-vision
problems that eyecare providers encounter all too commonly. The current range of tools at …

Highly pure phentolamine mesylate

DC Oniciu - US Patent 11,976,044, 2024 - Google Patents
This invention provides methods for synthesizing phentolamine mesylate from phentolamine
and methanesulfonic acid in the presence of acetone and water. The methods of the present …

Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders

WH Pitlick, AR Meyer, M Sooch, K Charizanis… - US Patent …, 2024 - Google Patents
US12016841B2 - Methods and compositions for treatment of presbyopia, mydriasis, and other
ocular disorders - Google Patents US12016841B2 - Methods and compositions for treatment of …

Effect of the chromaticity of stimuli on night vision disturbances

JJ Castro-Torres, M Casares-López… - Scientific Reports, 2024 - nature.com
The perception of halos and other night vision disturbances is a common complaint in
clinical practice. Such visual disturbances must be assessed in order to fully characterize …