DNA damage repair pathways in prostate cancer: a narrative review of molecular mechanisms, emerging biomarkers and therapeutic targets in precision oncology
Prostate cancer (PCa) has a distinct molecular signature, including characteristic
chromosomal translocations, gene deletions and defective DNA damage repair …
chromosomal translocations, gene deletions and defective DNA damage repair …
Exploring the integration of nanotechnology in the development and application of biosensors for enhanced detection and monitoring of colorectal cancer
As the third most severe cancer in the world, colorectal cancer (CRC) is of high concern to
global health concerns. Aging, unhealthy lifestyles, and genetic factors contribute to CRC …
global health concerns. Aging, unhealthy lifestyles, and genetic factors contribute to CRC …
Diagnostic performance of immunohistochemistry compared to molecular techniques for microsatellite instability and p53 mutation detection in endometrial cancer
S Streel, A Salmon, A Dheur, V Bours, N Leroi… - International Journal of …, 2023 - mdpi.com
Molecular algorithms may estimate the risk of recurrence and death for patients with
endometrial cancer (EC) and may impact treatment decisions. To detect microsatellite …
endometrial cancer (EC) and may impact treatment decisions. To detect microsatellite …
A 39 kb structural variant causing Lynch Syndrome detected by optical genome mapping and nanopore sequencing
PM Bjørnstad, R Aaløkken, J Åsheim… - European Journal of …, 2024 - nature.com
Lynch Syndrome (LS) is a hereditary cancer syndrome caused by pathogenic germline
variants in one of the four mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. It …
variants in one of the four mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. It …
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort
A Pantaleo, G Forte, F Cariola, AM Valentini, C Fasano… - Cancers, 2023 - mdpi.com
Simple Summary Lynch syndrome (LS) is an inherited genetic condition caused by germline
mutations in DNA mismatch repair (MMR) genes. It is associated with a predisposition to …
mutations in DNA mismatch repair (MMR) genes. It is associated with a predisposition to …
Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review
A Pantaleo, G Forte, C Fasano, M Lepore Signorile… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with
high mortality. Most patients present with an advanced stage of the disease, highlighting the …
high mortality. Most patients present with an advanced stage of the disease, highlighting the …
The Epithelial to Mesenchymal Transition in Colorectal Cancer Progression: The Emerging Role of Succinate Dehydrogenase Alterations and Succinate Accumulation
M Turano, R Vicidomini, F Cammarota, V D'Agostino… - Biomedicines, 2023 - mdpi.com
Colorectal cancer (CRC) stands as the third most significant contributor to cancer-related
mortality worldwide. A major underlying reason is that the detection of CRC usually occurs at …
mortality worldwide. A major underlying reason is that the detection of CRC usually occurs at …
Germline Variants in MLH1 and ATM Genes in a Young Patient with MSI-H in a Precancerous Colonic Lesion
A Nolano, GB Rossi, V D'Angelo, R Liccardo… - International Journal of …, 2023 - mdpi.com
Lynch syndrome (LS) is an autosomal dominant inherited disorder that primarily
predisposes individuals to colorectal and endometrial cancer. It is associated with …
predisposes individuals to colorectal and endometrial cancer. It is associated with …
Nanoliposome‐loaded phenolics from Salvia leriifolia Benth and its anticancer effects against induced colorectal cancer in mice
NS Nasrabadi, A Vedad, K Asadi… - Biotechnology and …, 2024 - Wiley Online Library
Colon cancer is one of the leading causes of death among various types of cancer. Despite
the significant progress made in cancer treatment, chemotherapy resistance and various …
the significant progress made in cancer treatment, chemotherapy resistance and various …
Biopsie colique et pathologie néoplasique épithéliale en pratique
D Chatelain - Revue Francophone des Laboratoires, 2023 - Elsevier
Résumé Cette mise au point sur les tumeurs épithéliales coliques permet d'aborder la prise
en charge de ces lésions par les pathologistes, les caractéristiques anatomopathologiques …
en charge de ces lésions par les pathologistes, les caractéristiques anatomopathologiques …