[HTML][HTML] Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase

N De La Iglesia, M Veiga-da-Cunha… - FEBS letters, 1999 - Elsevier
Glucokinase (GK), a key enzyme in the glucose homeostatic responses of the liver, changes
its intracellular localisation depending on the metabolic status of the cell. Rat liver GK and …

The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p

WEI TAN, AS ZOLOTUKHIN, J BEAR, DJ PATENAUDE… - Rna, 2000 - cambridge.org
Human TAP and Saccharomyces cerevisiae Mex67p belong to a family of proteins that
mediate mRNA export. Computer searches identified previously two Caenorhabditis …

Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs

J Bear, W Tan, AS Zolotukhin… - … and cellular biology, 1999 - Am Soc Microbiol
The nuclear export of the unspliced type D retrovirus mRNA depends on the cis-acting
constitutive transport RNA element (CTE) that has been shown to interact with the human …

[HTML][HTML] Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis

S Nakielny, G Dreyfuss - Current biology, 1998 - cell.com
Background: Nuclear protein import and export are mediated by receptor proteins that
recognize nuclear localization sequences (NLSs) or nuclear export sequences (NESs) and …

Splice choice antagonists as therapeutic agents

SA Newman, NB Bronstein - US Patent 7,402,434, 2008 - Google Patents
The invention relates to methods and reagents for influencing alternative RNA splicing in
living cells. More particularly, the invention relates to novel means for influencing RNA splice …

[HTML][HTML] Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1: localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of …

S Brown, MJ McGrath, LM Ooms, R Gurung… - Journal of Biological …, 1999 - ASBMB
We have cloned and characterized a novel isoform of the skeletal muscle LIM protein 1
(SLIM1), designated SLIMMER. SLIM1 contains an N-terminal single zinc finger followed by …

Molecular cloning and characterization of a novel member of the MAP kinase superfamily

Y Miyata, M Akashi, E Nishida - Genes to Cells, 1999 - Wiley Online Library
Background Members of the MAP kinase superfamily play important roles in a wide variety
of signal transduction pathways, and several members have been identified. However, the …

The molecular mechanism of transport of macromolecules through nuclear pore complexes

R Bayliss, AH Corbett, M Stewart - Traffic, 2000 - Wiley Online Library
Trafficking of macromolecules between nuclear and cytoplasmic compartments takes place
through the nuclear pore complexes (NPCs) of the nuclear envelope. Nuclear trafficking …

Mechanism Underlying the Iron-dependent Nuclear Export of the Iron-responsive Transcription Factor Aft1p in Saccharomyces cerevisiae

R Ueta, N Fujiwara, K Iwai… - Molecular biology of the …, 2007 - Am Soc Cell Biol
Aft1p is an iron-responsive transcriptional activator that plays a central role in maintaining
iron homeostasis in Saccharomyces cerevisiae. Aft1p is regulated primarily by iron-induced …

Regulation of nuclear import and export by the GTPase Ran

SM Steggerda, BM Paschal - International review of cytology, 2002 - Elsevier
This review focuses on the control of nuclear import and export pathways by the small
GTPase Ran. Transport of signal-containing cargo substrates is mediated by receptors that …