Poly (A)-binding protein II (PABP2) is an abundant nuclear protein that binds with high
affinity to nascent poly (A) tails, stimulating their extension and controlling their length. In the …

We identified the Schizosaccharomyces pombe mex67 gene (spmex67) as a multicopy
suppressor of rae1-167 nup184-1 synthetic lethality and the rae1-167 ts mutation …

We characterized cellular and molecular mechanisms involved in spermatogenesis
following short-term heat exposure of murine testis. For these studies, we utilized a …

Far1p is a bifunctional protein that is required to arrest the cell cycle and to establish cell
polarity during yeast mating. Far1p is localized predominantly in the nucleus but …

To better understand the development of ventral mesencephalic dopamine neurons, we
performed subtractive hybridization screens to find ventral mesencephalic genes expressed …

We have previously described HAP, a novel hnRNP protein that is identical both to SAF-B, a
component of the nuclear scaffold, and to HET, a transcriptional regulator of the gene for …

The heterogeneous nuclear ribonucleoprotein (hnRNP) family includes predominantly
nuclear proteins acting at different stages of mRNA metabolism. A characteristic feature of …

It has previously been shown that interaction of eukaryotic initiation factor 5A (eIF-5A) with
the Rev trans-activator protein of HIV-1 mediates the transport of unspliced or incompletely …

The mechanism of mRNA export is a complex issue central to cellular physiology. We
characterized previously yeast Gle1p, a protein with a leucine-rich (LR) nuclear export …

Casein kinases are involved in a variety of signaling pathways, and also in inflammation,
cancer, and neurological diseases. Therefore, they are regarded as potential therapeutic …