Molecular imaging agents: impact on diagnosis and therapeutics in oncology
ME Seaman, G Contino, N Bardeesy… - Expert reviews in …, 2010 - cambridge.org
Imaging has become a crucial tool in oncology throughout the course of disease detection
and management, and is an integral part of clinical trials. Anatomical and functional imaging …
and management, and is an integral part of clinical trials. Anatomical and functional imaging …
Imaging enzymes at work: metabolic mapping by enzyme histochemistry
CJF Van Noorden - Journal of Histochemistry & …, 2010 - journals.sagepub.com
For the understanding of functions of proteins in biological and pathological processes,
reporter molecules such as fluorescent proteins have become indispensable tools for …
reporter molecules such as fluorescent proteins have become indispensable tools for …
ABPP methodology: introduction and overview
MB Nodwell, SA Sieber - Activity-Based Protein Profiling, 2012 - Springer
Activity-based protein profiling (ABPP) is emerging as a mature method for chemically
interrogating the proteome of a cell. This chapter serves to introduce the reader to ABPP by …
interrogating the proteome of a cell. This chapter serves to introduce the reader to ABPP by …
Cathepsin B inhibitors: combining dipeptide nitriles with an occluding loop recognition element by click chemistry
J Schmitz, T Li, U Bartz… - ACS Medicinal Chemistry …, 2016 - ACS Publications
An active site mapping of human cathepsin B with dipeptide nitrile inhibitors was performed
for a combinatorial approach by introducing several points of diversity and stepwise …
for a combinatorial approach by introducing several points of diversity and stepwise …
Cathepsin B may be a potential biomarker in cervical cancer
D Wu, H Wang, Z Li, L Wang, F Zheng, J Jiang, Y Gao… - 2012 - digitum.um.es
Cathepsin B is a protease which is able to digest extracellular matrix. It is currently unknown
whether cathepsin B plays a role in cervical cancer development and progression. With Q …
whether cathepsin B plays a role in cervical cancer development and progression. With Q …
Photochemical Internalization Using Natural Anticancer Drugs, Antimetabolites, and Nanoformulations: A Systematic Study against Breast and Pancreatic Cancer Cell …
C Barnett, F Joubert, A Iliopoulou… - Molecular …, 2023 - ACS Publications
Photochemical internalization (PCI) is a novel, minimally invasive drug delivery technology
that facilitates the delivery of therapeutic molecules into the cytosol of cells. In this work, PCI …
that facilitates the delivery of therapeutic molecules into the cytosol of cells. In this work, PCI …
A novel high content imaging-based screen identifies the anti-helminthic niclosamide as an inhibitor of lysosome anterograde trafficking and prostate cancer cell …
ML Circu, SS Dykes, J Carroll, K Kelly, F Galiano… - PloS one, 2016 - journals.plos.org
Lysosome trafficking plays a significant role in tumor invasion, a key event for the
development of metastasis. Previous studies from our laboratory have demonstrated that the …
development of metastasis. Previous studies from our laboratory have demonstrated that the …
[HTML][HTML] Many roles of CCL20: emphasis on breast cancer
CCL20 or MIP3α is a small~ 8 kDa protein primarily expressed in the liver, colon, prostate,
cervix, and skin. The cellular receptor for CCL20 is CCR6. CCl20 unlike many other …
cervix, and skin. The cellular receptor for CCL20 is CCR6. CCl20 unlike many other …
Rhenium Inhibitors of Cathepsin B (ReO(SYS)X (Where Y = S, py; X = Cl, Br, SPhOMe-p)): Synthesis and Mechanism of Inhibition
R Mosi, IR Baird, J Cox, V Anastassov… - Journal of medicinal …, 2006 - ACS Publications
The synthesis of four new oxorhenium (V) complexes containing the “3+ 1” mixed-ligand
donor set, ReO (SYS) X (where Y= S, py; X= Cl, Br), is described. All of the complexes tested …
donor set, ReO (SYS) X (where Y= S, py; X= Cl, Br), is described. All of the complexes tested …
[HTML][HTML] Harnessing the immune system: an effective way to manage diffuse large B-cell lymphoma
N Visweshwar, JF Rico, R Killeen… - Journal of …, 2023 - ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) is a heterogenous hematological disorder with
malignant potential controlled by immunological characteristics of the tumor …
malignant potential controlled by immunological characteristics of the tumor …