Proline metabolism in cancer

P Geng, W Qin, G Xu - Amino Acids, 2021 - Springer
Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is
the only proteogenic secondary amino acid that is abundant in the body. Recent studies …

[HTML][HTML] Combating drug resistance in hepatocellular carcinoma: No awareness today, no action tomorrow

F Jing, X Li, H Jiang, J Sun, Q Guo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Hepatocellular carcinoma (HCC), the sixth most common cancer worldwide, is associated
with a high degree of malignancy and poor prognosis. Patients with early HCC may benefit …

Identification of novel prognostic targets in glioblastoma using bioinformatics analysis

X Yin, Q Wu, Z Hao, L Chen - Biomedical engineering online, 2022 - Springer
Background Glioblastoma (GBM) is the most malignant grade of glioma. Highly aggressive
characteristics of GBM and poor prognosis cause GBM-related deaths. The potential …

Deciphering the immunological and prognostic features of bladder cancer through platinum-resistance-related genes analysis and identifying potential therapeutic …

S Xiong, S Li, J Zeng, J Nie, T Liu, X Liu… - Frontiers in …, 2023 - frontiersin.org
Objectives To identify the molecular subtypes and develop a scoring system for the tumor
immune microenvironment (TIME) and prognostic features of bladder cancer (BLCA) based …

Zinc finger proteins and ATP‐binding cassette transporter‐dependent multidrug resistance

S Barzegar, S Pirouzpanah - European Journal of Clinical …, 2024 - Wiley Online Library
Background Multidrug resistance (MDR) remains a significant challenge in cancer treatment,
leading to poor clinical outcomes. Dysregulation of ATP‐binding cassette (ABC) transporters …

[HTML][HTML] Collagen type X alpha 1 (COL10A1) contributes to cell proliferation, migration, and invasion by targeting prolyl 4-hydroxylase beta polypeptide (P4HB) in …

W Yang, X Wu, F Zhou - Medical Science Monitor: International …, 2021 - ncbi.nlm.nih.gov
Background Breast cancer, a common malignant tumor, has been considered as the leading
cause of cancer-related death in women. Collagen type X alpha 1 (COL10A1) is …

Plasma proteome signature to predict the outcome of breast cancer patients receiving neoadjuvant chemotherapy

S Gwark, HS Ahn, J Yeom, J Yu, Y Oh, JH Jeong… - Cancers, 2021 - mdpi.com
Simple Summary The prognostic impact of plasma protein biomarkers in breast cancer
patients treated with neoadjuvant chemotherapy (NCT) was evaluated using a proteomics …

ARID1A loss induces P4HB to activate fibroblasts to support lung cancer cell growth, invasion, and chemoresistance

R Huang, D Wu, K Zhang, G Hu, Y Liu, Y Jiang… - Cancer …, 2024 - Wiley Online Library
Loss of AT‐interacting domain‐rich protein 1A (ARID1A) frequently occurs in human
malignancies including lung cancer. The biological consequence of ARID1A mutation in …

Protein disulfide isomerase A1‑associated pathways in the development of stratified breast cancer therapies

EY Bakker, M Fujii… - International …, 2022 - spandidos-publications.com
The oxidoreductase protein disulfide isomerase A1 (PDIA1) functions as a cofactor for many
transcription factors including estrogen receptor α (ERα), nuclear factor (NF)‑κB, nuclear …

Neutrophil transcriptional deregulation by the periodontal pathogen Fusobacterium nucleatum in gastric Cancer: a Bioinformatic study

T Zhou, X Meng, D Wang, W Fu, X Li - Disease Markers, 2022 - Wiley Online Library
Background. Infection with the periodontal pathogen Fusobacterium nucleatum (F.
nucleatum) has been associated with gastric cancer. The present study is aimed at …