The invention relates to engineered polypeptides comprising Fc variants and their uses.
More specifically, Fc variants are described exhibiting reduced effector function. These vari …

2005-08-23 Assigned to GENENTECH, INC. reassignment GENENTECH, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Provided are methods for identifying the presence or absence of a chromosome abnormality
by which a cell-free sample nucleic acid from a subject is analyzed. In certain embodiments …

Non-invasive prenatal testing is becoming a field of rapidly growing interest. Early detection
of pregnancy-related conditions, including complications during pregnancy and genetic …

Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The
antibodies are used to “tag” Her2 overexpressing tumors for elimination by the host immune …

US5869045A - Antibody conjugates reactive with human carcinomas - Google Patents
US5869045A - Antibody conjugates reactive with human carcinomas - Google Patents Antibody …

(56) References Cited 5,321,501 A 6/1994 Swanson et al. 5,325, 198 A 6/1994 Hartley et al.
US PATENT DOCUMENTS 5,336,178 A 8/1994 Kaplan et al. 5,346,689 A 9/1994 Peyman et …

The present invention relates generally to rotatable optical couplings, and more particularly
to a manually separable and re-connectable optical-electrical rotary joint. The invention …

The invention relates to an apparatus for in vivo imaging. More specifically, the present
invention relates to a catheter that incorporates an Optical Coherence Tomography (OCT) …

US7091321B2 - Enhancing the circulating half-life of antibody-based fusion proteins - Google
Patents US7091321B2 - Enhancing the circulating half-life of antibody-based fusion proteins …