Current advances in Zika vaccine development
Y Wang, L Ling, Z Zhang, A Marin-Lopez - Vaccines, 2022 - mdpi.com
Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …
Emerging viruses and current strategies for vaccine intervention
During the past decade several notable viruses have suddenly emerged from obscurity or
anonymity to become serious global health threats, provoking concern regarding their …
anonymity to become serious global health threats, provoking concern regarding their …
Sex differences in immunity: implications for the development of novel vaccines against emerging pathogens
A Fathi, MM Addo, C Dahlke - Frontiers in immunology, 2021 - frontiersin.org
Vaccines are one of the greatest public health achievements and have saved millions of
lives. They represent a key countermeasure to limit epidemics caused by emerging …
lives. They represent a key countermeasure to limit epidemics caused by emerging …
Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa
E Margolin, WA Burgers, ED Sturrock… - Nature Reviews …, 2020 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many …
resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many …
[HTML][HTML] Highly attenuated poxvirus-based vaccines against emerging viral diseases
B Perdiguero, P Pérez, L Marcos-Villar… - Journal of Molecular …, 2023 - Elsevier
Although one member of the poxvirus family, variola virus, has caused one of the most
devastating human infections worldwide, smallpox, the knowledge gained over the last 30 …
devastating human infections worldwide, smallpox, the knowledge gained over the last 30 …
Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome
A Fathi, C Dahlke, V Krähling, A Kupke… - Nature …, 2022 - nature.com
Vaccine development is essential for pandemic preparedness. We previously conducted a
Phase 1 clinical trial of the vector vaccine candidate MVA-MERS-S against the Middle East …
Phase 1 clinical trial of the vector vaccine candidate MVA-MERS-S against the Middle East …
Human mpox: Biology, epidemiology, therapeutic options, and development of small molecule inhibitors
H Tang, A Zhang - Medicinal Research Reviews, 2023 - Wiley Online Library
Although monkeypox (mpox) has been endemic in Western and Central Africa for 50 years,
it has not received sufficient prophylactic and therapeutical attention to avoid evolving into …
it has not received sufficient prophylactic and therapeutical attention to avoid evolving into …
Vaccinia virus attenuation by codon deoptimization of the A24R gene for vaccine development
MM Lorenzo, A Nogales, K Chiem, R Blasco… - Microbiology …, 2022 - Am Soc Microbiol
Poxviruses have large DNA genomes, and they are able to infect multiple vertebrate and
invertebrate animals, including humans. Despite the eradication of smallpox, poxvirus …
invertebrate animals, including humans. Despite the eradication of smallpox, poxvirus …
Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines
NA Prow, R Jimenez Martinez, JD Hayball… - Expert review of …, 2018 - Taylor & Francis
Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the
pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual …
pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual …
Poxviral ANKR/F-box proteins: substrate adapters for ubiquitylation and more
RJ Ingham, F Loubich Facundo, J Dong - Pathogens, 2022 - mdpi.com
Poxviruses are double-stranded DNA viruses that infect insects and a variety of vertebrate
species. The large genomes of poxviruses contain numerous genes that allow these viruses …
species. The large genomes of poxviruses contain numerous genes that allow these viruses …