New psychoactive substances: a review and updates

A Shafi, AJ Berry, H Sumnall… - Therapeutic …, 2020 - journals.sagepub.com
New psychoactive substances (NPS) are a heterogeneous group of substances. They are
associated with a number of health and social harms on an individual and societal level …

[HTML][HTML] Synthetic cathinones and neurotoxicity risks: a systematic review

G Daziani, AF Lo Faro, V Montana, G Goteri… - International Journal of …, 2023 - mdpi.com
According to the EU Early Warning System (EWS), synthetic cathinones (SCs) are the
second largest new psychoactive substances (NPS) class, with 162 synthetic cathinones …

Oxytocin receptors are expressed by glutamatergic prefrontal cortical neurons that selectively modulate social recognition

Y Tan, SM Singhal, SW Harden, KM Cahill… - Journal of …, 2019 - Soc Neuroscience
Social recognition, the ability to recognize individuals that were previously encountered,
requires complex integration of sensory inputs with previous experience. Here, we use a …

DARK classics in chemical neuroscience: cathinone-derived psychostimulants

SJ Simmons, JM Leyrer-Jackson… - ACS chemical …, 2018 - ACS Publications
Cathinone is a plant alkaloid found in khat leaves of perennial shrubs grown in East Africa.
Similar to cocaine, cathinone elicits psychostimulant effects which are in part attributed to its …

Functional networks and network perturbations in rodents

KH Chuang, FA Nasrallah - Neuroimage, 2017 - Elsevier
Synchronous low-frequency oscillation in the resting human brain has been found to form
networks of functionally associated areas and hence has been widely used to map the …

[HTML][HTML] Proposing a “brain health checkup (BHC)” as a global potential “standard of care” to overcome reward dysregulation in primary care medicine: Coupling …

ER Braverman, CA Dennen, MS Gold… - International Journal of …, 2022 - mdpi.com
In 2021, over 100,000 people died prematurely from opioid overdoses. Neuropsychiatric
and cognitive impairments are underreported comorbidities of reward dysregulation due to …

Functional connectivity of chronic cocaine use reveals progressive neuroadaptations in neocortical, striatal, and limbic networks

CA Orsini, LM Colon-Perez, SC Heshmati, B Setlow… - Eneuro, 2018 - eneuro.org
Brain imaging studies indicate that chronic cocaine users display altered functional
connectivity between prefrontal cortical, thalamic, striatal, and limbic regions; however, the …

[HTML][HTML] Longitudinal characterization and biomarkers of age and sex differences in the decline of spatial memory

M Febo, A Rani, B Yegla, J Barter, A Kumar… - Frontiers in Aging …, 2020 - frontiersin.org
The current longitudinal study examined factors (sex, physical function, response to novelty,
ability to adapt to a shift in light/dark cycle, brain connectivity), which might predict the …

[HTML][HTML] Synthetic cathinones induce cell death in dopaminergic SH-SY5Y cells via stimulating mitochondrial dysfunction

HS Leong, M Philp, M Simone, PK Witting… - International journal of …, 2020 - mdpi.com
Increasing reports of neurological and psychiatric complications due to psychostimulant
synthetic cathinones (SCs) have recently raised public concern. However, the precise …

[HTML][HTML] The new classes of synthetic illicit drugs can significantly harm the brain: A neuro imaging perspective with full review of MRI findings

S Creagh, D Warden, MA Latif… - Clinical radiology & …, 2018 - ncbi.nlm.nih.gov
Synthetic drugs contain substances that are pharmacologically similar to those found in
traditional illicit drugs. Some of the most commonly abused synthetic drugs include synthetic …