Tremendous progress has been made in our understanding of the molecular basis of
hearing and hearing loss. Through recent advances, we have begun to understand the …

Half of the cases with congenital impaired hearing are hereditary (HIH). HIH may occur as
part of a multisystem disease (syndromic HIH) or as disorder restricted to the ear and …

Introduction: The majority of hearing loss in children can be accounted for by genetic
causes. Non-syndromic hearing loss accounts for 80% of genetic hearing loss in children …

Background Hearing is a complex trait, but until now only a few genes are known to
contribute to variability of this process. In order to discover genes and pathways that underlie …

Nonsyndromic Hereditary Hearing Loss is a common disorder accounting for at least 60% of
prelingual deafness. GJB2 gene mutations, GJB6 deletion, and the A1555G mitochondrial …

Background: Hearing loss (HL) is the most frequent sensory birth defect in humans.
Autosomal recessive non-syndromic HL (ARNSHL) is the most common type of hereditary …

Nearly half the patients who are in specialized otoneurologic units exhibit psychiatric
disorders [1]. The disorders are most significant in patients who have the chief symptoms of …

Connexins are the building blocks of gap junctions. In forming a gap junction, six connexins
oligomerize to form a hexameric torus called a connexon. The number of gap junctions in a …

Since deafness is the most common sensorineural disorder in humans, better understanding
of the underlying causes is necessary to improve counseling and rehabilitation. A Dutch …

目的调查全国21 个地区聋哑学生SLC26A4 基因热点突变及其发病频率, 由此分析和推测中国
人大前庭水管综合征的流行病学状况. 方法调查对象来自全国21 个省市自治区的聋哑学校学生 …