[HTML][HTML] Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations

A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) represents 80–90% of all differentiated
thyroid carcinomas. PTC has a high rate of gene fusions and mutations, which can influence …

Scrutinizing the therapeutic and diagnostic potential of nanotechnology in thyroid cancer: Edifying drug targeting by nano-oncotherapeutics

E Ghazy, A Kumar, M Barani, I Kaur, A Rahdar… - Journal of Drug Delivery …, 2021 - Elsevier
The dearth of potential of diagnostic and treatment methods hinders the fight against tumors.
The advances in nanotechnology are emerging, expressing countless latent applications …

[HTML][HTML] Predictors and a prediction model for central cervical lymph node metastasis in papillary thyroid carcinoma (cN0)

X Gao, W Luo, L He, J Cheng, L Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Objectives To screen out the predictors of central cervical lymph node metastasis (CLNM) for
papillary thyroid carcinoma (PTC) and establish a prediction model to guide the operation of …

Mutational status may supersede tumor size in predicting the presence of aggressive pathologic features in well differentiated thyroid cancer

K Semsar-Kazerooni, GB Morand… - … -Head & Neck …, 2022 - journals.sagepub.com
Background In clinical practice, thyroid tumor size plays a critical role in the staging of
thyroid malignancies and in the selection of nodules that should undergo ultrasound-guided …

[HTML][HTML] BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma

X Chen, S Lin, Y Lin, S Wu, M Zhuo, A Zhang… - Journal of Translational …, 2022 - Springer
Background Papillary thyroid carcinoma (PTC) is one of most prevalent malignant endocrine
neoplasms, and it is associated with a high frequency of BRAF gene mutations, which lead …

Profile of BRAFV600E, BRAFK601E, NRAS, HRAS, and KRAS Mutational Status, and Clinicopathological Characteristics of Papillary Thyroid Carcinoma in …

AS Harahap, I Subekti, SS Panigoro… - The Application of …, 2023 - Taylor & Francis
Introduction BRAF V600E and RAS mutations are the most common gene mutations in
papillary thyroid carcinoma (PTC) that may be correlated with its biological behavior. There …

[HTML][HTML] TERT Promoter Mutations Are an Independent Predictor of Distant Metastasis in Middle Eastern Papillary Thyroid Microcarcinoma

SK Parvathareddy, AK Siraj, K Iqbal, Z Qadri… - Frontiers in …, 2022 - frontiersin.org
Background Papillary thyroid microcarcinomas (PTMCs) have been attributed to the recent
increased incidence of thyroid cancer. Although indolent, a subset of PTMC could potentially …

[HTML][HTML] BRAF V600E and novel somatic mutations in thyroid cancer of Libyan patients

H Tounsi-Guettiti, H Traina, IB Ayed… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
Background: Thyroid cancer (TC) is a common endocrine malignancy that frequently
harbours the oncogenic V600E BRAF mutation. This mutation has received considerable …

[HTML][HTML] Methylation-driven gene PLAU as a potential prognostic marker for differential thyroid carcinoma

M Wu, B Wei, SL Duan, M Liu, DJ Ou-Yang… - Frontiers in Cell and …, 2022 - frontiersin.org
Purpose: Aberrant DNA methylation plays a crucial role in the tumorigenesis of differentiated
thyroid cancer (DTC); nevertheless, the factors leading to the local and regional recurrence …

A computational approach to assessing the prognostic implications of BRAF and RAS mutations in patients with papillary thyroid carcinoma

T Haghzad, B Khorsand, S Adeleh Razavi, M Hedayati - Endocrine, 2024 - Springer
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer, posing a growing
clinical challenge. PTC exhibits two age-related peaks, with established risk factors …