Liquid biopsy by ctDNA in liver transplantation for colorectal cancer liver metastasis

CJ Wehrle, R Raj, N Aykun, D Orabi, B Estfan… - Journal of …, 2023 - Elsevier
Introduction Colorectal cancer is a leading cause of cancer-related death worldwide.
Metastatic liver disease develops in 50% of cases and drives patient outcomes. Although the …

The impact of COVID-19 pandemic in the diagnosis and management of colorectal cancer patients

MJ Domper-Arnal, G Hijos-Mallada… - Therapeutic advances …, 2022 - journals.sagepub.com
The novel coronavirus disease 2019 (COVID-19) pandemic has posed an unprecedented
challenge to healthcare systems worldwide, causing downscaling of almost all other …

Advances in the management of pancreatic cancer

M Del Chiaro, T Sugawara, SD Karam… - Bmj, 2023 - bmj.com
Pancreatic cancer remains among the malignancies with the worst outcomes. Survival has
been improving, but at a slower rate than other cancers. Multimodal treatment, including …

[HTML][HTML] Role of ctDNA for the detection of minimal residual disease in resected non-small cell lung cancer: a systematic review

M Verzè, M Pluchino, A Leonetti… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Operable stage I-III non-small cell lung cancer (NSCLC) has a high risk of
recurrence, mainly due to remnant clones of the disease defined as minimal residual …

[HTML][HTML] Incidental detection of FGFR3 fusion via liquid biopsy leading to earlier diagnosis of urothelial carcinoma

Q Huang, I Mitsiades, H Dowst… - NPJ Precision …, 2023 - nature.com
The rising utilization of circulating tumor DNA (ctDNA) assays in Precision Oncology may
incidentally detect genetic material from secondary sources. It is important that such findings …

[HTML][HTML] Total Neoadjuvant Treatment for Locally Advanced Rectal Cancer Patients: Where Do We Stand?

V Daprà, M Airoldi, M Bartolini, R Fazio… - International Journal of …, 2023 - mdpi.com
The therapeutic landscape in locally advanced rectal cancer (LARC) has undergone a
significant paradigm shift in recent years with the rising adoption of total neoadjuvant …

[HTML][HTML] Diagnostic and therapeutic updates in leptomeningeal disease

MA Roy-O'Reilly, T Lanman, A Ruiz, D Rogawski… - Current oncology …, 2023 - Springer
Abstract Purpose of Review Leptomeningeal disease (LMD) is a devastating complication of
advanced metastatic cancer associated with a poor prognosis and limited treatment options …

Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

AJ Widman, M Shah, A Frydendahl, D Halmos… - Nature Medicine, 2024 - nature.com
In solid tumor oncology, circulating tumor DNA (ctDNA) is poised to transform care through
accurate assessment of minimal residual disease (MRD) and therapeutic response …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer 2023 Supplement

SJ Langenfeld, BR Davis, JD Vogel… - Diseases of the Colon …, 2024 - journals.lww.com
The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring
highquality patient care by advancing the science, prevention, and management of …

Perioperative therapy for resectable non–small-cell lung cancer: Weighing Options for the present and future

D Uprety, HJ West - JCO Oncology Practice, 2023 - ascopubs.org
Anatomic surgical resection followed by cisplatin-based platinum-doublet adjuvant
chemotherapy has been a long-standing standard of care for patients with early-stage …