The coming of age of liquid biopsy in neuro-oncology

G Berzero, V Pieri, P Mortini, M Filippi, G Finocchiaro - Brain, 2023 - academic.oup.com
The clinical role of liquid biopsy in oncology is growing significantly. In gliomas and other
brain tumours, targeted sequencing of cell-free DNA (cfDNA) from CSF may help differential …

Liquid biopsy in colorectal cancer: Onward and upward

S Torresan, M de Scordilli, M Bortolot… - Critical Reviews in …, 2023 - Elsevier
Colorectal cancer (CRC) remains a leading cause of cancer-related deaths worldwide. In
recent years, liquid biopsy has emerged as one of the most interesting areas of research in …

[HTML][HTML] Unraveling the potential clinical utility of circulating tumor DNA detection in colorectal cancer—evaluation in a nationwide Danish cohort

TV Henriksen, C Demuth, A Frydendahl, J Nors… - Annals of …, 2024 - Elsevier
Background Increasingly, circulating tumor DNA (ctDNA) is proposed as a tool for minimal
residual disease (MRD) assessment. Digital PCR (dPCR) offers low analysis costs and …

Emerging roles of circulating tumor DNA for increased precision and personalization in radiation oncology

N Earland, K Chen, NP Semenkovich… - Seminars in Radiation …, 2023 - Elsevier
Recent breakthroughs in circulating tumor DNA (ctDNA) technologies present a compelling
opportunity to combine this emerging liquid biopsy approach with the field of radiogenomics …

Liquid biopsy for precision adjuvant chemotherapy in colon cancer

C Montagut, J Vidal - New England Journal of Medicine, 2022 - Mass Medical Soc
Liquid biopsy, the detection of tumor-related DNA in the peripheral blood, is currently the
best available technological tool to improve clinical decision making in precision oncology. 1 …

Serum NY-ESO-1 antibody as a predictive biomarker for postoperative recurrence of gastric cancer: A multicenter prospective observational study

T Saito, Y Kurokawa, K Fujitani, R Kawabata… - British Journal of …, 2024 - nature.com
Background No reliable marker has been identified to predict postoperative recurrence of
gastric cancer. We designed a clinical trial to investigate the utility of serum NY-ESO-1 …

Implications of High Tumor Burden on Chimeric Antigen Receptor T-Cell Immunotherapy: A Review

M Ventin, G Cattaneo, L Maggs, S Arya, X Wang… - JAMA …, 2024 - jamanetwork.com
Importance Chimeric antigen receptor (CAR) T-cell therapy has redefined the therapeutic
landscape of several hematologic malignant tumors. Despite its clinical efficacy, many …

Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies

C Martin-Alonso, S Tabrizi, K Xiong, T Blewett… - Science, 2024 - science.org
Liquid biopsies enable early detection and monitoring of diseases such as cancer, but their
sensitivity remains limited by the scarcity of analytes such as cell-free DNA (cfDNA) in blood …

Recent Advances in Therapeutic Strategies to Improve Colorectal Cancer Treatment

WH Gmeiner - Cancers, 2024 - mdpi.com
Simple Summary Colorectal cancer is a leading cause of cancer mortality, and its incidence
is rapidly increasing worldwide. Colorectal cancer is considered a single entity based on …

Leveraging comprehensive cancer registry data to enable a broad range of research, audit and patient support activities

B Lee, L Gately, SW Lok, B Tran, M Lee, R Wong… - Cancers, 2022 - mdpi.com
Simple Summary Registry data has the potential to support a broad range of research, audit
and education initiatives. Here, we describe the experience and learnings of a series of …