Cancer is a predominant cause of mortality all over the world. Lung, prostate, and colorectal
cancer are the more frequent in men while breast and colorectal have a high incidence in …

Project Optimus is a US Food and Drug Administration Oncology Center of Excellence
initiative aimed at reforming the dose selection and optimization paradigm in oncology drug …

In the paradigm shift related to rectal cancer treatment, we have to understand a variety of
new emerging topics to provide appropriate treatment for individual patients as precision …

Simple Summary After the surgical removal of colorectal cancer (CRC), residual cancer cells
undetectable by standard blood tests and imaging studies are responsible for cancer …

The purpose of precision dosing is to increase the chances of therapeutic success in
individual patients. This is achieved in practice by adjusting doses to reach precision dosing …

Minimal Residual Disease (MRD) detection has emerged as an independent factor in
clinical and pathological cancer assessment offering a highly effective method for predicting …

Simple Summary Immunotherapy is emerging as an improved systemic treatment for select
patients with advanced unresectable hepatocellular carcinoma. An objective response is …

Plasma circulating tumor DNA (ctDNA) sequencing has demonstrated clinical utility for tumor
molecular profiling at initial diagnosis or tumor progression in advanced solid cancers and is …

Up to 430,000 cases of bladder cancer are diagnosed each year worldwide. A proposed
method for non-invasive monitoring has been to utilize a “liquid biopsy.” Liquid biopsy has …

Purpose This was a review of circulating tumor DNA (ctDNA) in patients with peritoneal
metastases from colorectal cancer. Methods We searched the PubMed database for studies …