Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …

Antibiotic resistance presents an incessant threat to our drug armamentarium that
necessitates novel approaches to therapy. Over the past several decades, investigation of …

Introduction Linezolid can cause serious adverse effects including thrombocytopenia and
anemia. Here, we focus specifically on linezolid-related hematological toxicity in adult …

Aims The purpose of the study was to assess the status of emerging therapeutic drug
monitoring (TDM) of anti‐infective agents in Australian hospitals. Methods A nationwide …

Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and
individualized treatment have been challenged since its approval. With the in-depth clinical …

Background Linezolid is a broad-spectrum antimicrobial with limited use due to toxicity. This
study aimed to evaluate linezolid toxicity in a large multicentre cohort. Secondary objectives …

In patients that are admitted to intensive care units (ICUs), the clinical outcome of severe
infections depends on several factors, as well as the early administration of chemotherapies …

Background Effectiveness, safety, tolerability, and adherence are critical considerations in
shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include …

Drug dosing in obese patients continues to be challenging due to a lack of high‐quality
evidence to guide dosing recommendations. We first published guidance for antibiotic …